All Free Veterinary Science MCQs with Answers

• A. Quaternary ammonium compound
• B. Small inorganic electrolyte
• C. Highly water-soluble sugar
• D. Highly lipid-soluble acidic drug

Explanation: Many lipid-soluble acidic drugs bind extensively to albumin, so displacement by another drug can temporarily increase the free active…

• A. Cardiac arrhythmias
• B. Severe bone marrow aplasia
• C. Permanent cataract formation
• D. Acute pancreatic rupture

Explanation: Digoxin toxicity commonly produces gastrointestinal signs and potentially serious cardiac arrhythmias because it alters myocardial…

• A. Complete renal filtration
• B. A smaller free fraction in plasma
• C. Rapid entry into cerebrospinal fluid
• D. Unrestricted tissue penetration

Explanation: Only the unbound fraction of a drug is readily available for distribution, metabolism and renal filtration.

• A. Dopamine
• B. Glutamic acid
• C. Gamma-aminobutyric acid
• D. Norepinephrine

Explanation: Benzodiazepines enhance gamma-aminobutyric acid activity at GABA-A receptors, increasing neuronal inhibition.

• A. Cholesterol formation
• B. Peptidoglycan breakdown
• C. Bile acid synthesis
• D. Folate synthesis

Explanation: Sulfonamides inhibit dihydropteroate synthase, an enzyme required for bacterial folate synthesis.

• A. Fomepizole
• B. Praziquantel
• C. Naloxone
• D. Protamine

Explanation: Fomepizole inhibits alcohol dehydrogenase and prevents formation of toxic ethylene glycol metabolites.

• A. Ligand-gated chloride channel
• B. Voltage-gated sodium channel
• C. Voltage-gated calcium channel
• D. ATP-sensitive potassium channel

Explanation: Pyrethroids delay closure of voltage-gated sodium channels, causing repetitive nerve firing and paralysis in susceptible arthropods.

• A. One half-life
• B. Two half-lives
• C. Four to five half-lives
• D. Ten to twelve half-lives

Explanation: For drugs with first-order elimination, about 94 to 97 percent of steady state is reached after four to five half-lives.

• A. Collecting duct concentration
• B. Glomerular filtration
• C. Tubular reabsorption
• D. Tubular secretion

Explanation: Active tubular secretion moves some drugs from peritubular capillaries into the renal tubular lumen for excretion.

• A. Acidic urine
• B. Alkaline urine
• C. Neutral plasma
• D. Alkaline bile

Explanation: Weak bases become more protonated and ionized in acidic urine, which reduces passive tubular reabsorption and may increase excretion.

• A. Receptor down-regulation
• B. Receptor up-regulation
• C. Permanent enzyme inhibition
• D. Reduced drug absorption

Explanation: Long-term receptor blockade can cause compensatory up-regulation or increased sensitivity of receptors.

• A. Enrofloxacin
• B. Amikacin
• C. Erythromycin
• D. Sulfadiazine

Explanation: Erythromycin binds the 50S subunit and interferes with bacterial translocation during protein synthesis.

• A. Desmopressin
• B. Vitamin K1
• C. Fomepizole
• D. Protamine sulfate

Explanation: Protamine sulfate forms an inactive complex with heparin and reverses its anticoagulant action.

• A. A disease transmitted naturally between vertebrate animals and humans
• B. A disease transmitted only between domestic animals
• C. A disease caused only by arthropod vectors
• D. A disease transmitted from humans to humans only

Explanation: A zoonosis is an infection that passes naturally between vertebrate animals and humans.

• A. Dairy cattle
• B. Domestic dog
• C. Household cat
• D. Domestic poultry

Explanation: In Pakistan, human rabies is most commonly associated with bites from infected domestic dogs.

• A. Horses and donkeys
• B. Cattle and buffaloes
• C. Sheep and goats
• D. Chickens and turkeys

Explanation: Brucella melitensis primarily infects sheep and goats and can cause severe disease in humans.

• A. A moist ulcer with a blue-green discharge
• B. A painful vesicular rash on the trunk
• C. A circular ringworm lesion with central clearing
• D. A painless black eschar with surrounding edema

Explanation: Cutaneous anthrax typically begins as a papule and progresses to a painless ulcer with a characteristic black eschar and marked…

• A. Sheep
• B. Dog
• C. Human
• D. Cattle

Explanation: Dogs and other canids carry the adult tapeworm in the intestine and shed eggs in their feces, making them definitive hosts.

• A. 100°C for 1 second
• B. 63°C for 30 minutes
• C. 72°C for 15 seconds
• D. 50°C for 5 minutes

Explanation: High-temperature short-time pasteurization commonly heats milk to 72°C for at least 15 seconds.

• A. Wait for symptoms before seeking medical care
• B. Close the wound immediately with tight sutures
• C. Apply soil to stop the bleeding
• D. Wash the wound thoroughly with soap and running water

Explanation: Prompt and thorough washing with soap and running water reduces the amount of virus at the wound site.