Which drug is most likely to undergo extensive binding to plasma albumin and show displacement interactions with other drugs?
Correct answer: D. Highly lipid-soluble acidic drug
- A. Quaternary ammonium compound
- B. Small inorganic electrolyte
- C. Highly water-soluble sugar
- D. Highly lipid-soluble acidic drug
Explanation
Many lipid-soluble acidic drugs bind extensively to albumin, so displacement by another drug can temporarily increase the free active fraction. Water-soluble substances and permanent charged compounds generally show different distribution patterns.
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Covers how drugs act in animals, including pharmacokinetics, pharmacodynamics, routes of administration, dosage forms, adverse effects and drug interactions. Major groups include antimicrobials, antiparasitics, analgesics, anaesthetics, anti-inflammatory drugs, hormones and cardiovascular medicines, with attention to withdrawal periods and species differences.
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