The bronchodilator action of aminophylline is mainly related to inhibition of which enzyme?
Correct answer: C. Phosphodiesterase
- A. Cyclooxygenase
- B. Monoamine oxidase
- C. Phosphodiesterase
- D. Acetylcholinesterase
Explanation
Aminophylline, a theophylline preparation, inhibits phosphodiesterase and increases intracellular cyclic AMP, promoting bronchial smooth muscle relaxation. Cyclooxygenase inhibitors are mainly anti-inflammatory analgesics.
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Covers how drugs act in animals, including pharmacokinetics, pharmacodynamics, routes of administration, dosage forms, adverse effects and drug interactions. Major groups include antimicrobials, antiparasitics, analgesics, anaesthetics, anti-inflammatory drugs, hormones and cardiovascular medicines, with attention to withdrawal periods and species differences.
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