Levamisole causes paralysis of susceptible nematodes mainly by acting on which receptor system?
Correct answer: B. Nicotinic acetylcholine receptors
- A. GABA chloride channels
- B. Nicotinic acetylcholine receptors
- C. Serotonin 5-HT1 receptors
- D. Muscarinic acetylcholine receptors
Explanation
Levamisole stimulates nematode nicotinic acetylcholine receptors, producing sustained contraction followed by paralysis. Its action differs from ivermectin, which increases chloride ion conductance in parasites.
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Covers how drugs act in animals, including pharmacokinetics, pharmacodynamics, routes of administration, dosage forms, adverse effects and drug interactions. Major groups include antimicrobials, antiparasitics, analgesics, anaesthetics, anti-inflammatory drugs, hormones and cardiovascular medicines, with attention to withdrawal periods and species differences.
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