Pyrethroid insecticides exert their principal toxic effect on arthropods by altering the function of which ion channel?
Correct answer: B. Voltage-gated sodium channel
- A. Ligand-gated chloride channel
- B. Voltage-gated sodium channel
- C. Voltage-gated calcium channel
- D. ATP-sensitive potassium channel
Explanation
Pyrethroids delay closure of voltage-gated sodium channels, causing repetitive nerve firing and paralysis in susceptible arthropods. Their primary target is not the calcium or potassium channels listed.
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Covers how drugs act in animals, including pharmacokinetics, pharmacodynamics, routes of administration, dosage forms, adverse effects and drug interactions. Major groups include antimicrobials, antiparasitics, analgesics, anaesthetics, anti-inflammatory drugs, hormones and cardiovascular medicines, with attention to withdrawal periods and species differences.
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