Free Central Nervous System Drugs MCQs with Answers

107 Central Nervous System Drugs MCQs from Pharmacology, each with the correct answer and a written explanation of why it is correct. Free and unlimited, with no account needed.

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  • A. Valproic acid.
  • B. Carbamazepine.
  • C. Ethosuximide.
  • D. Phenytoin

Explanation: Long-term phenytoin therapy may cause gingival hyperplasia, hirsutism, coarse facial features, and vitamin-D-related osteomalacia.

Correct answer: Phenytoin
  • A. Phenobarbital.
  • B. Meprobamate
  • C. Chlordiazepoxide
  • D. Triazolam
  • E. Zolpidum

Explanation: Phenobarbital induces hepatic microsomal enzymes, increasing the metabolism of warfarin and other drugs and potentially reducing their…

Correct answer: Phenobarbital.
  • A. Zolpidem
  • B. Buspiron.
  • C. Midazolam
  • D. Triazolam
  • E. Phenobarbital

Explanation: Buspirone is a non-sedating anxiolytic used specifically for long-term treatment of generalized anxiety disorder.

Correct answer: Buspiron.
  • A. Cough suppression
  • B. Anti-emesis
  • C. Miosis
  • D. Truncal rigidityPain Management

Explanation: Opioids commonly cause nausea and vomiting rather than anti-emesis, although they do produce cough suppression, miosis, and sometimes…

Correct answer: Anti-emesis
  • A. Natrexone
  • B. Nalbuphine
  • C. Butorphanol
  • D. Pentazonice

Explanation: Naltrexone, misspelled in the options as “Natrexone,” is a pure opioid receptor antagonist.

Correct answer: Natrexone
  • A. Zolmitriptan
  • B. Zileuton
  • C. Zolpiden
  • D. Zalcitabine

Explanation: Zolpidem is a short-acting non-benzodiazepine sedative-hypnotic used for insomnia.

Correct answer: Zolpiden
  • A. Alprazolam
  • B. Diazepam
  • C. Buspiron
  • D. Phenobarbital

Explanation: Buspirone relieves generalized anxiety through serotonin 5-HT1A mechanisms and does not act directly on the GABAergic system.

Correct answer: Buspiron
  • A. Aspirin
  • B. Phenytoin
  • C. Chloromphenicol
  • D. Cyclosporine

Explanation: Long-term phenytoin therapy can impair folate absorption or metabolism, producing folic acid deficiency and sometimes megaloblastic…

Correct answer: Phenytoin
  • A. Acetaminophen
  • B. Acetylsalicylic acid
  • C. Phenylbutazone
  • D. NaproxenConsult Online Doctors

Explanation: Acetaminophen provides analgesia without significantly inhibiting platelet function, making it safer in a hemophiliac than aspirin or…

Correct answer: Acetaminophen
  • A. Nicotinic cholinergic receptors
  • B. Glutamate receptors
  • C. GABA receptors
  • D. Glucocorticoid receptors

Explanation: GABA receptor activation increases inhibitory neurotransmission in the brain, reducing neuronal excitability and anxiety.

Correct answer: GABA receptors
  • A. patients having fever
  • B. patients having asthma
  • C. patients having amoebic dysentery
  • D. Patient having bronchitisGet Study Guides

Explanation: Ibuprofen can precipitate bronchospasm in patients with aspirin-sensitive asthma because cyclooxygenase inhibition shunts arachidonic acid…

Correct answer: patients having asthma
  • A. 1 ml / min
  • B. 2.5 ml / min
  • C. 1 mg / min
  • D. 2.5 mg / min

Explanation: Intravenous diazepam should be administered slowly, commonly at no more than about 1 mL per minute, to reduce respiratory and…

Correct answer: 1 ml / min
  • A. 1 min
  • B. 2 min
  • C. 3-5 min
  • D. 10 minBook Pain Specialists

Explanation: Succinylcholine has an ultra-short action because it is rapidly hydrolysed by plasma pseudocholinesterase, with muscle relaxation usually…

Correct answer: 3-5 min
  • A. Peptic ulcer
  • B. Person suffering form chicken pox or small pox
  • C. Hemorrhage
  • D. All of the above

Explanation: Aspirin increases gastrointestinal bleeding and is contraindicated in peptic ulcer disease or active haemorrhage; it should also be…

Correct answer: All of the above
  • A. codeine
  • B. Methadone
  • C. Alphaprodine
  • D. Pentazocine

Explanation: Methadone is a long-acting opioid used for opioid-substitution treatment because it prevents withdrawal and reduces craving without the…

Correct answer: Methadone
  • A. Contraindicated
  • B. Low safety
  • C. Can be used safely
  • D. Not much useTry Prep Courses

Explanation: Barbiturates have a narrow therapeutic index, so respiratory depression and excessive sedation make them relatively low-safety drugs in…

Correct answer: Low safety
  • A. Meprobamate
  • B. Pentobarbital
  • C. Trimethadione
  • D. Phenytoin

Explanation: Phenytoin is a classic treatment for generalized tonic-clonic, or grand mal, seizures because it limits sustained high-frequency neuronal…

Correct answer: Phenytoin
  • A. Antibiotics
  • B. Salicylates
  • C. Barbiturates
  • D. Phenothiazines

Explanation: Phenothiazines block dopamine D2 receptors in the nigrostriatal pathway, causing extrapyramidal symptoms such as dystonia, akathisia and…

Correct answer: Phenothiazines
  • A. Folic acid deficiency
  • B. Alzhiemer's disease
  • C. Cushing's syndrome
  • D. Vitamin C deficiencyConsult Online Doctors

Explanation: Phenytoin increases folate metabolism and can reduce folic acid levels during long-term treatment, sometimes causing megaloblastic…

Correct answer: Folic acid deficiency
  • A. D-tubocurarin
  • B. Diazepam
  • C. Beclofen
  • D. Mephensin

Explanation: D-tubocurarine produces skeletal muscle relaxation by blocking nicotinic receptors at the neuromuscular junction, which is a peripheral…

Correct answer: D-tubocurarin

Central Nervous System Drugs MCQs: common questions

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There are 107 Central Nervous System Drugs MCQs in the Pharmacology bank, shown 20 to a page with the correct answer and an explanation on each.

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