Which of the following drugs causes extra pyramidal symptoms_____________?

Correct answer: D. Phenothiazines

  • A. Antibiotics
  • B. Salicylates
  • C. Barbiturates
  • D. Phenothiazines

Explanation

Phenothiazines block dopamine D2 receptors in the nigrostriatal pathway, causing extrapyramidal symptoms such as dystonia, akathisia and parkinsonism. The other listed drug groups are not classically associated with this adverse-effect pattern.

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