Free Central Nervous System Drugs MCQs with Answers

• A. Carbamazepine
• B. Topiramate
• C. Ethosuxamide
• D. Phenobarbitone

Explanation: Topiramate is an established preventive treatment for migraine and is also an antiepileptic drug.

• A. Head injury
• B. Acute myocardial infarcation
• C. Acute abdominal pain before diagnosis
• D. Bronchial asthma

Explanation: Morphine may be used for severe pain associated with acute myocardial infarction, so this is the exception.

• A. Thiopentone
• B. Ketamine
• C. Propofol
• D. Fentanyl

Explanation: Ketamine produces bronchodilation and is useful for induction in patients at risk of bronchospasm.

• A. Platalets <80,000
• B. Patient on aspirin
• C. Patient on oral anticoagulants
• D. Raised intracranial pressure

Explanation: Aspirin alone usually does not contraindicate spinal or epidural anaesthesia, although bleeding risk must still be assessed.

• A. Propofol
• B. Diazepam
• C. Droperidol
• D. Midazolam

Explanation: Propofol has a rapid onset and very rapid recovery because it is rapidly redistributed and metabolised, with less residual drowsiness than…

• A. Methoxyflurane
• B. Sevoflurane
• C. Desflurane
• D. Isoflurane

Explanation: Sevoflurane is preferred for inhalational induction in children because it is non-irritant and has a relatively rapid onset.

• A. Ketamine
• B. Thiopentone
• C. Tentanyl
• D. Nitrous oxide

Explanation: Ketamine may cause emergence reactions such as vivid dreams, hallucinations and delirium because of its dissociative action.

• A. Cocaine
• B. Etomidate
• C. Cyclopropane
• D. Procaine

Explanation: Cocaine causes marked sympathetic vasoconstriction by blocking norepinephrine reuptake, so it is the exception.

• A. Daroperidol + Fentanyl
• B. Deroperidol + Ketamine
• C. Droperiodl + Ether
• D. Droperiodl + Thiopental sodium + Nitrous oxide

Explanation: Neuroleptanalgesia combines a neuroleptic, droperidol, with a potent opioid analgesic, fentanyl.

• A. Harpes David
• B. Harvey william
• C. Horace wells
• D. Hunter John

Explanation: Horace Wells introduced nitrous oxide for dental analgesia after observing its pain-reducing effects.

• A. Cocaine
• B. Procaine
• C. Lidocaine
• D. Tetracaine

Explanation: Cocaine is a local anaesthetic that also produces powerful central stimulation, including cerebral cortical excitation, by blocking…

• A. Short general anesthetic agent
• B. Local anesthetic agent
• C. Antidepressive agent
• D. Hypnotic agent

Explanation: Ketamine is a short-acting dissociative general anaesthetic that produces analgesia, amnesia and a trance-like state.

• A. Behavioral problem
• B. Sensitizes the heart to adrenaline
• C. Prolonged difficult induction
• D. Tachycardia and or arrhythmias

Explanation: Nitrous oxide may cause excitement, disinhibition and other behavioural changes, especially during induction or recovery.

• A. Thiopental
• B. Halothane
• C. Ethyl Ether
• D. Nitrous oxide

Explanation: Halothane sensitises the myocardium to catecholamines, making ventricular arrhythmias a recognised complication.

• A. Analgesia
• B. Excitation
• C. Surgical anesthesia
• D. Respiratory arrest

Explanation: A 50% nitrous oxide and oxygen mixture produces analgesia but is not strong enough to produce surgical anaesthesia in an unmedicated…

• A. Procaine
• B. Tetracaine
• C. Lidocaine
• D. Benzocaine

Explanation: Procaine is poorly lipid-soluble and penetrates intact mucous membranes inadequately, so it is unsuitable for surface anaesthesia.

• A. A good analgesic but a poor anesthetic
• B. A good anesthetic but a poor analgesic
• C. A good analgesic and a good anesthetic
• D. A poor analgesic and a poor anesthetic

Explanation: Nitrous oxide provides useful analgesia and anxiolysis but is a weak general anaesthetic, so it cannot reliably produce surgical…

• A. Lignocaine
• B. Procaine
• C. Tetracaine
• D. Benzocaine

Explanation: Procaine has poor penetration through mucosa and is therefore not useful for surface anaesthesia.

• A. Halothane
• B. Isoflurane
• C. Sevoflurane
• D. Desflurane

Explanation: Halothane tends to cause bradycardia or little change in heart rate, whereas isoflurane, sevoflurane and desflurane commonly increase…

• A. Isoflurane
• B. Ether
• C. Halothane
• D. Proplofol

Explanation: Halothane sensitises the myocardium to circulating catecholamines, increasing the risk of ventricular arrhythmias.