Which of the following drugs when used for prolonged period in the maintenance treatment of tonic-clonic seizures can lead to increased metabolism of warfarin like drugs?
Correct answer: A. Phenobarbital.
- A. Phenobarbital.
- B. Meprobamate
- C. Chlordiazepoxide
- D. Triazolam
- E. Zolpidum
Explanation
Phenobarbital induces hepatic microsomal enzymes, increasing the metabolism of warfarin and other drugs and potentially reducing their effects. The benzodiazepines and zolpidem listed do not produce this prominent enzyme-inducing interaction.
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