Free Cardiovascular Drugs MCQs with Answers

• A. Propranolol
• B. Timolol
• C. Metoprolol
• D. Labetalol

Explanation: Labetalol blocks both beta receptors and alpha-1 receptors, producing reduced heart rate and peripheral vasodilation.

• A. Sodium Nitro prusside
• B. Hydrallazine
• C. Nifedipine
• D. Nitrates

Explanation: Hydralazine and nifedipine predominantly dilate arterioles, while nitrates mainly dilate veins and reduce venous return.

• A. Angina pectoris
• B. Cardiac arrhythmia
• C. Cardiac failure
• D. Myocardial infarction

Explanation: Beta blockers are generally avoided in acute or decompensated cardiac failure because their negative inotropic effect can worsen pump…

• A. Direct action on smooth muscle
• B. Slows SA node conductivity
• C. Blocks arrhythmia
• D. Increases perfusion to heart

Explanation: Nitroglycerin releases nitric oxide, increasing cyclic GMP and directly relaxing vascular smooth muscle, especially veins.

• A. Hypokalemia
• B. Hyperuricemia
• C. Hypercalcemia
• D. Hyponatremia

Explanation: Frusemide increases urinary calcium loss and therefore tends to cause hypocalcaemia, not hypercalcaemia.

• A. The effect is more pronounced in venous
• B. High membrane penetrability
• C. Poorly suited for oral administration
• D. All of the above

Explanation: Nitroglycerin is highly lipid-soluble and rapidly crosses membranes, but extensive first-pass metabolism makes it poorly suited to…

• A. Mixture of sulphated polypeptide
• B. Known to cause idiopathic thrombocytosis
• C. Half-life is 90 min
• D. Decrease action of prothrombin III

Explanation: Unfractionated heparin has a short, dose-dependent half-life of roughly 60 to 90 minutes.

• A. Hydralazine
• B. a-Methldopa
• C. Nifedipine
• D. Enlapril

Explanation: Enalapril, an ACE inhibitor, is contraindicated in pregnancy because it can impair fetal renal development and cause fetal renal failure…

• A. Quinapril
• B. Fosinopril
• C. Benzopril
• D. Lisinopril

Explanation: Quinapril, fosinopril and benazepril are prodrugs converted to active diacid metabolites.

• A. Dopamine
• B. dobutamine
• C. Digoxin
• D. Doxepin

Explanation: Dopamine, dobutamine and digoxin increase myocardial contractility through beta1 stimulation or enhanced intracellular calcium.

• A. May cause hyperkalaemia in diabetic patients
• B. Contraindicated in pregnancy
• C. Contraindicated in diabetic nephropathy
• D. NSAIDs may impair its hypotensive effect

Explanation: ACE inhibitors are useful in diabetic nephropathy because they reduce intraglomerular pressure and proteinuria.

• A. Sodium nitrate
• B. Epinephrine
• C. Nitroglycerina
• D. Isosorbide dinitrateGet Study Guides

Explanation: Sublingual nitroglycerin is commonly used to terminate an acute angina attack because it rapidly releases nitric oxide, dilates veins and…

• A. Saralosin
• B. Diltiazem
• C. Coptopril
• D. Spirino lactone

Explanation: “Coptopril” is a misspelling of captopril, an ACE inhibitor that lowers angiotensin II and aldosterone formation.

• A. Propranolol
• B. Hydralazine
• C. A thiazide diuretic
• D. Gauanethidine

Explanation: Guanethidine depletes noradrenaline from sympathetic nerve terminals and alters neuronal uptake, making responses to injected…

• A. Ephedrine
• B. Reserpine
• C. Methyldopa
• D. Thiazole diuretics

Explanation: Ephedrine increases sympathetic activity and can raise blood pressure, so it is not an antihypertensive drug.

• A. Less tolerance develops
• B. Sublingual absorption is better
• C. Longer duration of action
• D. Direct coronary vasodilatory action is more

Explanation: Isosorbide 5-mononitrate has a longer duration of action and more reliable oral bioavailability than isosorbide dinitrate because it…

• A. Alpha methyl DOPA
• B. Prazosin
• C. Clonidine
• D. Propranolol

Explanation: Prazosin selectively blocks post-synaptic alpha-1 receptors, relaxing arterioles and veins to lower blood pressure.

• A. Calcium channel blockers
• B. Alpha methyl dopa
• C. Beta blockers
• D. Pentoxifyline

Explanation: Pentoxifylline improves red-cell flexibility and peripheral blood flow in vascular disease but is not a standard antihypertensive drug.

• A. Hypertension
• B. Angina pectoris
• C. Atrial fibrillation
• D. Congestive heart failure

Explanation: Quinidine is a class IA antiarrhythmic historically used for atrial fibrillation and other supraventricular arrhythmias.

• A. Increases cAMP
• B. Direct Vasodilator
• C. Calcium channel blocker
• D. Block the sympathetic flow at hypothalamus

Explanation: Sodium nitroprusside releases nitric oxide, which increases vascular cGMP and directly relaxes vascular smooth muscle in both arteries and…