Which of the following antihypertensive agents in most likely to cause an exaggerated response to an injected catecholamine_____________?
Correct answer: D. Gauanethidine
- A. Propranolol
- B. Hydralazine
- C. A thiazide diuretic
- D. Gauanethidine
Explanation
Guanethidine depletes noradrenaline from sympathetic nerve terminals and alters neuronal uptake, making responses to injected catecholamines unusually exaggerated. Propranolol, hydralazine and thiazides do not characteristically produce this interaction.
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