Isosorbide 5 - mononitrate is preferred because____________?
Correct answer: C. Longer duration of action
- A. Less tolerance develops
- B. Sublingual absorption is better
- C. Longer duration of action
- D. Direct coronary vasodilatory action is more
Explanation
Isosorbide 5-mononitrate has a longer duration of action and more reliable oral bioavailability than isosorbide dinitrate because it avoids first-pass metabolism. Its main advantage is not greater direct coronary vasodilation.
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