Free Antimicrobial Agents MCQs with Answers
144 Antimicrobial Agents MCQs from Pharmacology, each with the correct answer and a written explanation of why it is correct. Free and unlimited, with no account needed.
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144 questions · page 7 of 8
- A. Rifampicin induce the metabolism of contra ceptive
- B. Rifampicin simulates gonadotropin relase from pituitary
- C. Rifampicin decrease the secretion of progestin
- D. Rifampicin antagonize the action of oral contraceptiveOrder Infection Tests
Explanation: Rifampicin strongly induces hepatic drug-metabolizing enzymes, increasing the breakdown of estrogen and progestin in oral contraceptives.
Correct answer: Rifampicin induce the metabolism of contra ceptive- A. Rifampicin
- B. INH
- C. Pyrazinamide
- D. Ethambutol
Explanation: Ethambutol inhibits arabinosyl transferase and may produce dose-related optic neuritis, presenting with reduced visual acuity or red-green…
Correct answer: Ethambutol123. Among the drugs given below, which is LEAST likely to be implicated in drug induced hepatitis ?
- A. Isoniazid
- B. Streptomycin
- C. Ripampicin
- D. Pyrazinamide
Explanation: Isoniazid, rifampicin, and pyrazinamide are all well-known causes of antituberculous drug-induced hepatitis.
Correct answer: Streptomycin- A. Hypo Kalemia
- B. Hyperkalemia
- C. Hypermagnesemia
- D. Hyponatremia
Explanation: Amphotericin B damages renal tubular function, causing potassium and magnesium wasting, so hypokalemia is a characteristic toxicity.
Correct answer: Hypo Kalemia- A. Ampicillin
- B. Dicloxacillin
- C. Erythromycin
- D. Any of the above
Explanation: Dicloxacillin resists staphylococcal penicillinase and is well absorbed orally, making it useful for infections caused by…
Correct answer: Dicloxacillin- A. Penicillin
- B. Streptomycin
- C. Garamycin
- D. Kanamycin
Explanation: Penicillin resistance usually develops through a stepwise accumulation of mutations, unlike streptomycin resistance, which can arise from…
Correct answer: Penicillin- A. Benzyl penicillin
- B. Benzathine penicillin
- C. Procaine pencillin
- D. Penicillin V / Phenoxymethyl penicillin
Explanation: Penicillin V, or phenoxymethylpenicillin, is acid-stable and can therefore be given orally.
Correct answer: Penicillin V / Phenoxymethyl penicillin- A. Antiemetic
- B. Antiviral
- C. Antifungal
- D. antibiotic
Explanation: Ototoxicity and nephrotoxicity are characteristic dose-related toxicities of aminoglycoside antibiotics, especially gentamicin, amikacin…
Correct answer: antibiotic- A. Amoxicillin
- B. Carbenicillin
- C. Cloxacillin
- D. Phenoxymethy penicillin
Explanation: Carbenicillin has poor and unreliable oral absorption, so it is administered parenterally.
Correct answer: Carbenicillin- A. Side effects of drugs
- B. Cost of therapy
- C. Dosage of drugs
- D. Development of drug resistance
Explanation: Tuberculosis is treated with several drugs simultaneously because resistant bacilli may already be present or may emerge during treatment.
Correct answer: Development of drug resistance- A. pencillin
- B. Tetracycline
- C. Cephalosporins
- D. Erythromycin
Explanation: Tetracyclines bind calcium and other polyvalent cations to form poorly absorbed chelates, so milk and calcium-containing antacids reduce…
Correct answer: Tetracycline- A. Increase effectivity against gram-negative organisms
- B. Inhibition of B-lactamases
- C. Increase the effectiveness against delta lactamase producing organism
- D. Increase effectivity against gram-positive organisms
Explanation: Clavulanic acid is a beta-lactamase inhibitor that protects ampicillin from enzymatic hydrolysis and thereby extends its activity against…
Correct answer: Inhibition of B-lactamases- A. Diloxane
- B. Metronidazole
- C. Chloroquine
- D. Cefaclor
Explanation: Metronidazole reaches the intestinal wall and extraintestinal tissues, so it treats invasive intestinal and hepatic amoebiasis.
Correct answer: Metronidazole- A. Rifampicin
- B. Ethambutol
- C. INH
- D. Streptomycin
Explanation: Rifampicin produces orange-red discoloration of urine, sweat, saliva and tears because its strongly coloured metabolite is excreted in…
Correct answer: Rifampicin- A. Amoxycillin
- B. Cloxacillin
- C. Ampicillin
- D. Penicillin G
Explanation: Cloxacillin is a penicillinase-resistant penicillin designed to withstand staphylococcal beta-lactamase.
Correct answer: Cloxacillin- A. Ampicillin
- B. Tetracyclin
- C. Erythromycin
- D. Co-trimoxazole
Explanation: Erythromycin inhibits CYP3A4, reducing terfenadine metabolism and increasing its plasma concentration.
Correct answer: Erythromycin- A. Amphotericin
- B. Nystatin
- C. Ketoconazole
- D. Clotrimazole
Explanation: Clotrimazole is mainly used topically or as an oral troche for mucosal candidiasis and is not a standard treatment for intestinal…
Correct answer: Clotrimazole- A. Inhibits DNA gyrase
- B. Inhibits Bacterial protein synthesis
- C. Inhibits bacterial cell wall synthesis
- D. Inhibits intake of folic acid
Explanation: Quinolones inhibit bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and repair.
Correct answer: Inhibits DNA gyrase- A. Children
- B. Pregnancy
- C. Renal failure
- D. All of the above
Explanation: Tetracyclines bind calcium in developing teeth and bones, so they are avoided in children and pregnancy; conventional tetracyclines can…
Correct answer: All of the above- A. Erythromycin
- B. Streptomycin
- C. Tetracycline
- D. Chloramphenicol
Explanation: Erythromycin is the classic alternative for many infections in patients with penicillin hypersensitivity because it inhibits bacterial…
Correct answer: Erythromycin