Oral contraceptive failure occurs in a patient on Rifampicin because of____________?

Correct answer: A. Rifampicin induce the metabolism of contra ceptive

  • A. Rifampicin induce the metabolism of contra ceptive
  • B. Rifampicin simulates gonadotropin relase from pituitary
  • C. Rifampicin decrease the secretion of progestin
  • D. Rifampicin antagonize the action of oral contraceptiveOrder Infection Tests

Explanation

Rifampicin strongly induces hepatic drug-metabolizing enzymes, increasing the breakdown of estrogen and progestin in oral contraceptives. The resulting lower hormone concentrations can cause contraceptive failure.

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