A patient has seasonal allergic rhinitis and is on terfenadine, He develps cardiac arrhythmias after a course of antibiotics. Which of the following antibiotic could have been given_____________?
Correct answer: C. Erythromycin
- A. Ampicillin
- B. Tetracyclin
- C. Erythromycin
- D. Co-trimoxazole
Explanation
Erythromycin inhibits CYP3A4, reducing terfenadine metabolism and increasing its plasma concentration. The resulting QT prolongation can trigger serious ventricular arrhythmias such as torsades de pointes.
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Practise Antimicrobial Agents
144 free Antimicrobial Agents MCQs from Pharmacology, each with the correct answer and an explanation. Unlimited attempts, no account needed.
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