Clavulanic acid added to ampicillin causes_____________?
Correct answer: B. Inhibition of B-lactamases
- A. Increase effectivity against gram-negative organisms
- B. Inhibition of B-lactamases
- C. Increase the effectiveness against delta lactamase producing organism
- D. Increase effectivity against gram-positive organisms
Explanation
Clavulanic acid is a beta-lactamase inhibitor that protects ampicillin from enzymatic hydrolysis and thereby extends its activity against beta-lactamase-producing bacteria. The relevant mechanism is enzyme inhibition, not direct antibacterial activity.
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