All Free Pharmacology MCQs with Answers

• A. Succinylcholine
• B. Pancuronium
• C. Mivacurum
• D. Decamethonium

Explanation: Mivacurium is a short-acting, non-depolarising neuromuscular blocker, rapidly hydrolysed by plasma cholinesterase.

• A. Chlorozoxazone
• B. Methocarbomol
• C. Succinyl choline
• D. Cortisopradol

Explanation: Succinylcholine acts peripherally at nicotinic neuromuscular junctions and produces skeletal muscle paralysis.

• A. Nicotinic
• B. Muscarinic
• C. Alpha 1 and 2
• D. Beta 1 and 2

Explanation: Muscarinic receptors are activated by acetylcholine and blocked by atropine.

• A. Increases salivary secretions
• B. Decrease salivary secreations
• C. Indicator dye for sialography
• D. Medication for over function

Explanation: Sialogogues stimulate salivary secretion, either by directly activating cholinergic pathways or by promoting parasympathetic activity.

• A. With xylocaine
• B. Post extraction socket
• C. Anaphylactin shock
• D. Angina in dental chair
• E. Both B & D

Explanation: Adrenaline is useful with local anaesthetics and in anaphylactic shock, but it should not be used routinely in an angina patient or placed…

• A. Hypertension
• B. Hypotension
• C. Doesn't release histamine
• D. Oral route of administration is the best route

Explanation: Curare blocks nicotinic receptors at the neuromuscular junction and can cause hypotension, partly because some preparations release…

• A. Hypertension
• B. Amxiety
• C. Peripheral Vascular disease
• D. Benign Prostatic hypertrophy

Explanation: Alpha-adrenoceptor blockers are used in hypertension, peripheral vascular disease and benign prostatic hypertrophy by reducing vascular or…

• A. Doxacurim
• B. Decamethonium
• C. Rocuronium
• D. Mivacurium

Explanation: Decamethonium is a depolarizing neuromuscular blocker that produces persistent end-plate depolarization.

• A. Sedatives
• B. Vasoconstrictors
• C. Antisialogogues
• D. Local anaesthetic

Explanation: Antisialogogues such as atropine reduce secretions through muscarinic blockade, which can raise intraocular pressure and worsen…

• A. Epinephrine
• B. Lidnocaine
• C. Hydrocortisone
• D. Dicoumarol

Explanation: Topical epinephrine causes local vasoconstriction through alpha-adrenoceptor stimulation, reducing blood flow and helping control oral…

• A. Bupivacaine
• B. Procaine
• C. Lidocaine
• D. None of the above

Explanation: Bupivacaine, procaine, and lidocaine generally produce local vasodilation rather than vasoconstriction, which can increase systemic…

• A. These agents decrease transmembrane calcium current associated in a smooth muscle with long-lasting relaxation
• B. and in a cardiac muscle with a reduction in contractility
• C. These agents has a moderate reflex and vascular dilative action caused by the stimulation of sensitive nerve endings
• D. Beneficial effects of these agents are related primarily to their hemodynamic effects - decreased heart rate, blood
• E. pressure, and contractility - which decrease myocardial oxygen requirements at rest and during exercise
• F. These agents increase the permeability of K channels, probably ATP-dependent K channels, that results in stabilizing the membrane potential of excitable cells near the resting potential Drugs & Medications

Explanation: Potassium-channel openers increase K⁺ permeability, often through ATP-sensitive channels, causing membrane hyperpolarisation and…

• A. Fever
• B. Post myocardial infarction
• C. Venous thrombosis
• D. Gout

Explanation: Aspirin is useful as an antipyretic and for secondary prevention after myocardial infarction, while low-dose antiplatelet therapy may…

• A. peptic ulcer
• B. Bleeding defects
• C. Carcinoma
• D. A & B

Explanation: Prolonged aspirin use inhibits protective gastric prostaglandins, promoting peptic ulceration, and irreversibly impairs platelet…

• A. Agranulocytosis
• B. Hemolytic anemia
• C. Aplastic anemia
• D. Hypoprothrombinemia

Explanation: Aspirin can cause hypoprothrombinemia, especially at high doses or with prolonged use, by interfering with vitamin K-dependent clotting…

• A. Vitamin K
• B. Barbiturates
• C. Acetominophen
• D. Acetyl salicylic acid

Explanation: Aspirin irreversibly inhibits platelet cyclooxygenase, reducing thromboxane A2 and prolonging bleeding or clotting-related tests.

• A. It inhibits thromboxanes
• B. It stimulates Prostacyclins
• C. It is a vasodilator
• D. Ithelps in reducing inflammatory aggregate

Explanation: Low-dose aspirin irreversibly blocks platelet thromboxane A2 synthesis, reducing platelet aggregation and the risk of further coronary…

• A. Indomenthacin
• B. Salicylates
• C. Dypyradimole
• D. Phenobarbitone

Explanation: Indomethacin, aspirin and related salicylates inhibit platelet thromboxane-dependent aggregation, while dipyridamole also has antiplatelet…

• A. It delay onset of labour
• B. Causes pulmonary hypertension of newborn
• C. Readily croses placental barrier
• D. All of these

Explanation: Salicylates cross the placenta and, particularly late in pregnancy, may delay labour and increase the risk of premature closure of the…

• A. Aspirin
• B. Paracetamol
• C. Diclofenac sodium
• D. Ibuprofen

Explanation: Paracetamol is generally safe in heart failure at therapeutic doses because it does not significantly promote sodium and water retention.