All Free Pharmacology MCQs with Answers

• A. Mg Causes constipation, Al causes diarrhoea
• B. Mg Causes Diarrhoea, Al Causes Constipation
• C. Mg act as buffering agent and Al antagonize its action
• D. Both increase gastric motility

Explanation: Magnesium salts tend to cause diarrhoea, whereas aluminium salts cause constipation.

• A. Anticancer drug
• B. Antibiotic
• C. Antiarrythmic
• D. Immunosuppresant

Explanation: Cyclosporine suppresses T-cell activation by inhibiting calcineurin and reducing interleukin-2 production, so it is used as an…

• A. Iron dextran
• B. Iron Sorbitol Citrate Solution
• C. ferrous Sulphate
• D. ferrous Humourate

Explanation: Iron dextran is a parenteral iron preparation that can be administered by both deep intramuscular and intravenous routes.

• A. Astrigents
• B. Styptics
• C. Haemostatics
• D. All of the above

Explanation: Haemostatics promote or assist the stoppage of bleeding; styptics are local haemostatics, and astringents can reduce bleeding by…

• A. Agranulocytosis
• B. Aplastic anaemia
• C. Aaemolysis
• D. Leukaemia

Explanation: Agranulocytosis, aplastic anaemia, and haemolysis are recognised serious adverse drug reactions.

• A. Phenobarbitone
• B. Phenytoin
• C. Diazepam
• D. Carbemezipine

Explanation: Intravenous diazepam is commonly used to rapidly control convulsions caused by poisoning, including many drug toxicities.

• A. Respiratory alkalosis
• B. Haemorrhage
• C. Hepatic necrosis
• D. Gastric Ulceration

Explanation: The major dose-related toxicity of acetaminophen overdose is hepatic necrosis caused by accumulation of the toxic metabolite NAPQI when…

• A. They depress ALA synthase
• B. They inhibit ALA synthase
• C. They induce heme oxygenase
• D. They inhibit heme oxygenase

Explanation: Barbiturates induce hepatic ALA synthase, increasing porphyrin precursor production and potentially precipitating acute porphyria.

• A. Renal failure
• B. Liver failure
• C. Respiratory failure
• D. Convulsions

Explanation: Acute barbiturate poisoning produces profound central nervous system depression, with respiratory depression and failure being the major…

• A. Formaldehyde
• B. Acetaldehyde
• C. Propanaldehyde
• D. Butanaldehyde

Explanation: Ethanol is first oxidised to acetaldehyde, a reactive metabolite that can cause facial flushing, tachycardia and headache, especially in…

• A. Crystalluria
• B. Rye's syndrome
• C. Kernicterus
• D. None of the above

Explanation: Aspirin or salicylate exposure in children, particularly during a viral illness, is associated with Reye syndrome, involving acute…

• A. EDTA
• B. DMSA
• C. BAL
• D. Penicillamine

Explanation: The blue gingival line, constipation, reduced reflexes, drowsiness, and seizures indicate severe lead poisoning with encephalopathy.

• A. Penicillamine
• B. E.D.T.A
• C. Desferrixamine
• D. B.A.L

Explanation: Dimercaprol, also called British anti-Lewisite or BAL, chelates arsenic and is the classic antidote for significant arsenic poisoning.

• A. ASA
• B. Acetyl morphine
• C. Pentazocine
• D. Propoxyphene

Explanation: Heroin is diacetylmorphine, formed by acetylating morphine at two hydroxyl groups.

• A. Kala azar
• B. Pernicious anaemia
• C. Pain control
• D. Thalassemia

Explanation: Desferrioxamine is an iron-chelating agent used chronically to remove excess iron in thalassemia and acutely in iron poisoning.

• A. Oraganophosphate poisoning
• B. Paracetamol poisoning
• C. Mushroom poisoning
• D. Atropine poisoning

Explanation: Bronchodilation, fever, tachycardia, constipation and other antimuscarinic effects form the classic atropine poisoning syndrome, often…