Clotting time is most like to be prolonged by the administration of____________?

Correct answer: D. Acetyl salicylic acid

  • A. Vitamin K
  • B. Barbiturates
  • C. Acetominophen
  • D. Acetyl salicylic acid

Explanation

Aspirin irreversibly inhibits platelet cyclooxygenase, reducing thromboxane A2 and prolonging bleeding or clotting-related tests. Vitamin K and barbiturates do not produce this antiplatelet effect, while acetaminophen has little effect on platelet function at usual doses.

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