Free Oral Manifestations of Systemic Disease MCQs with Answers

• A. All of the above
• B. Brown tumours
• C. Cystic changes
• D. Generalized demineralization

Explanation: Excess parathyroid hormone causes generalized bone demineralization, osteitis fibrosa, and localized giant-cell-rich brown tumours with…

• A. Hypoparathyroidism
• B. Hyperthyroidism
• C. Rickets
• D. Syphilis

Explanation: Hyperthyroidism can disturb tooth formation and eruption, especially causing accelerated eruption, without the enamel hypoplasia…

• A. Eosinophilic granuloma
• B. Hand Schuller - Christian disease
• C. All of the above
• D. Letterer - Siwe disease

Explanation: Histiocytosis X, now grouped under Langerhans cell histiocytosis, historically included eosinophilic granuloma, Hand-Schüller-Christian…

• A. Vitamin B
• B. Niacin
• C. Pantothenic acid
• D. Riboflavin

Explanation: Riboflavin deficiency causes a magenta or purplish tongue, angular cheilitis and fissuring at the mouth corners.

• A. Niacin
• B. Vit - B1
• C. Vit - C
• D. Vit - K

Explanation: Niacin deficiency causes pellagra, classically producing glossitis, stomatitis and other mucosal lesions.

• A. Periodontosis
• B. Hyperpituitarism
• C. Hypothyroidism
• D. Hypoadrenalism

Explanation: Hyperpituitarism in an adult causes acromegaly, with enlargement of the jaws and increased spacing between teeth.

• A. Gingival Fibres
• B. Periodontal ligament
• C. Blood Vessels of the gingiva
• D. Epithelial lining of the mucosa

Explanation: Vitamin C is essential for collagen synthesis, so its deficiency strongly affects gingival fibres, periodontal ligament and gingival blood…

• A. Enamel
• B. Dentin
• C. Cementum
• D. Periodontal Ligament

Explanation: Vitamin A deficiency disrupts ameloblast function during tooth development and therefore most notably produces enamel hypoplasia.

• A. Defective osteoid+ normal mineralization
• B. normal osteoid + defective mineralization
• C. abnormal osteoid + abnormal mineralization
• D. normal osteoid an demineralization

Explanation: Osteomalacia results from defective mineralization of a normally formed osteoid matrix, usually due to vitamin D deficiency or resistance.

• A. Nieman pick disease
• B. Marble bone diasease
• C. Hand-Schuller Christian disease
• D. Polyostotic fibrous dysplasia

Explanation: Hand-Schüller-Christian disease, a form of Langerhans cell histiocytosis, can cause destructive jaw lesions with loose teeth and central…

• A. Is an autoimmune disease
• B. causes hypopigmentation
• C. Causes hypertension
• D. Steroids are contraindicated

Explanation: Addison disease is commonly autoimmune and causes adrenal insufficiency with hypotension and mucosal or skin hyperpigmentation.

• A. Hypophosphatasia
• B. Vitamin -D resistant rickets
• C. Hypervitaminosis-A
• D. Vitamin-A deficiency

Explanation: Vitamin D-resistant rickets produces defective dentin mineralization, including globular dentin, enlarged pulp horns and sometimes loss of…

• A. RBC
• B. Fibroblast
• C. Lymphocytes
• D. WBC

Explanation: Reilly bodies are abnormal cytoplasmic granules seen in leukocytes, especially lymphocytes, in Hurler syndrome.

• A. cadmium
• B. lead
• C. aluminium
• D. copper

Explanation: Hepatolenticular degeneration, or Wilson disease, results from impaired copper excretion and copper deposition in the liver, brain and…

• A. Micrognathia
• B. Large tongue
• C. Hypoglycaemia
• D. Crowded teeth

Explanation: Excess growth hormone in acromegaly enlarges soft tissues, producing macroglossia and often prognathism or spacing of teeth.

• A. citric acid
• B. phytates
• C. Retinoic acid
• D. Oxalates

Explanation: Phytates and oxalates bind calcium in the gut and reduce its absorption, whereas citric acid promotes absorption; retinoic acid is not a…

• A. Loss of laminadura
• B. Osteitis fibrosa cystica
• C. Erosion below the duramater of skull
• D. All of the above

Explanation: Hyperparathyroidism causes increased bone resorption, classically producing loss of the lamina dura, osteitis fibrosa cystica and erosive…

• A. Neurofibromatosis
• B. Pigmented villonodular synovitis
• C. Osteomalacia
• D. Hyperparathyroidism

Explanation: Brown tumours are reparative giant-cell lesions caused by marked osteoclastic activity in hyperparathyroidism.

• A. Vitamin D
• B. Vitamin C
• C. Vitamin B
• D. Vitamin E & D

Explanation: Vitamin C deficiency causes defective collagen formation, leading to swollen or bleeding gingiva, poor wound healing, anemia and tooth…

• A. Pemphigus
• B. Erythema multiforme
• C. prophyria
• D. Lichen planus

Explanation: Porphyria can cause red or reddish-brown fluorescent urine or body fluids because porphyrins fluoresce under ultraviolet light.