A five-year old child presents with chronic bed wetting and bilateral loose deciduous first molars. His mother says that she want to drink of water several times during each night. Which of the following is the most likely diagnosis ?
Correct answer: C. Hand-Schuller Christian disease
- A. Nieman pick disease
- B. Marble bone diasease
- C. Hand-Schuller Christian disease
- D. Polyostotic fibrous dysplasia
Explanation
Hand-Schüller-Christian disease, a form of Langerhans cell histiocytosis, can cause destructive jaw lesions with loose teeth and central diabetes insipidus, producing nocturnal thirst and bed-wetting. The combination of bone lesions and diabetes insipidus is the key clue.
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