Free Oral Manifestations of Systemic Disease MCQs with Answers

• A. Yellow and brown stains only in enamel
• B. Yellow and brown stains in enamel and dentin
• C. Yellow and brown stains only in dentin
• D. Only yellow stain in enamel

Explanation: Tetracycline binds calcium during tooth mineralisation, so it becomes incorporated into both enamel and dentin.

• A. High-protein diet
• B. Erythromycin
• C. penicillins
• D. Tetracyclines

Explanation: Tetracyclines cross the placenta and enter breast milk, and in children they bind calcium in developing teeth, causing intrinsic yellow…

• A. Haemosiderin
• B. Biliribin
• C. Methemoglobin
• D. Myoglobin

Explanation: Iron overload in haemochromatosis leads to deposition of haemosiderin, producing bronze or brown pigmentation of tissues.

• A. Burtonian line
• B. pigmentation is areas of inflammation
• C. Gingiva
• D. Blackish line in the mucosa

Explanation: Bismuth intoxication produces a dark bismuth line or pigmentation, most noticeable in areas of gingival inflammation.

• A. Sensitivity to acrylic resin
• B. All of the above
• C. Hereditary
• D. Using ACE inhibitors

Explanation: Angioedema may be allergic, drug-induced such as with ACE inhibitors, or hereditary due to C1-inhibitor pathway abnormalities.

• A. Cherubism
• B. Cretinism
• C. Lead poisoning
• D. Pierre Robin Syndrome

Explanation: Lead poisoning can cause neurobehavioral or emotional changes, hypersalivation, pallor, and a blue-gray Burtonian line along the gingiva.

• A. cushing's syndrome
• B. addison's disease
• C. peutz jeghers syndrome
• D. albright syndrome

Explanation: Peutz–Jeghers syndrome, Addison disease, and Albright syndrome commonly produce mucocutaneous pigmentation.

• A. Hyperthyroidism
• B. Hyperpituitarism
• C. Hypopituitarism
• D. Hyperparathyroidism

Explanation: Hyperpituitarism in adults causes acromegaly, with enlargement of the mandible and widening of interdental spaces.

• A. Niacin
• B. Cyanocobalamine
• C. Thiamine
• D. Riboflavin

Explanation: Wernicke encephalopathy results from thiamine, or vitamin B1, deficiency and classically causes confusion, ataxia, and ophthalmoplegia.

• A. Osteomalacia
• B. Vit. D resistant Rickets
• C. Juvenile periodontitis
• D. Hypophosphatasia

Explanation: Hypophosphatasia results from deficient alkaline phosphatase activity, causing defective bone and cementum mineralisation and urinary…

• A. Vit A
• B. Vit K
• C. Folic acid
• D. Cyanacobalamin

Explanation: Cyanocobalamin, or vitamin B12, deficiency can cause neurological problems through defective myelin synthesis, including paraesthesia and…

• A. Peutz-jeghers syndrome
• B. Cushing syndrome
• C. Addision's syndrome
• D. Albright syndrome

Explanation: Peutz–Jeghers, Addison syndrome, and Albright syndrome are classic causes of oral and cutaneous pigmentation.

• A. Eosinophilic
• B. Osteosarcoma
• C. Giant cell granuloma
• D. Multiple myeloma

Explanation: An older patient with anaemia, back pain, and multiple punched-out radiolucencies strongly suggests multiple myeloma, caused by malignant…

• A. proteins
• B. phytic Acid
• C. lactose
• D. Acidity

Explanation: Phytic acid binds calcium in the intestine to form poorly absorbed phytates, thereby reducing calcium absorption.

• A. Cu
• B. K
• C. Zn
• D. Cr

Explanation: Zinc deficiency can cause hypogonadism, growth or developmental delay, impaired taste, and reduced smell.

• A. Acromegaly
• B. Hyperthyroidism
• C. Hypoparathyroidism
• D. Pituitary gigantism

Explanation: Pituitary gigantism, caused by excess growth hormone before epiphyseal closure, may produce generalized macrodontia.

• A. Acute nicotinic acid deficiency
• B. Any periodontal disease
• C. Vitamin A deficiency
• D. Ascorbic acid deficiency

Explanation: Acute nicotinic acid, or niacin, deficiency causes pellagra with a painful beefy-red glossitis.

• A. Apthous ulcers
• B. Keratocyst
• C. Brown tumor of hyper parathyroidism
• D. Dentigerous cyst

Explanation: Brown tumours of hyperparathyroidism contain numerous osteoclast-type giant cells within a fibrovascular stroma.

• A. Addison's disease
• B. Von-Recklinghausen disease
• C. Hyperthyroidism
• D. Hypothyroidism

Explanation: Childhood hypothyroidism delays tooth eruption and root resorption while macroglossia produces the characteristic large tongue.

• A. Zinc
• B. Mercury
• C. Lead
• D. Bismuth

Explanation: Acrodermatitis enteropathica is caused by defective zinc absorption or severe zinc deficiency.