All Free Oral Pathology and Medicine MCQs with Answers

• A. hypoplasia of incisor and molar, VIII nerve motor paralysis and peg laterals.
• B. Hypoplasia of incisor and molar, V nerve motor paralysis interstitial keratitis
• C. Hypoplasia of incisor and molar, VIII nerve deafness and interstitial keratitis
• D. None of the above

Explanation: Hutchinson's triad of congenital syphilis consists of Hutchinson incisors and abnormal first molars, interstitial keratitis, and…

• A. Hyaline degeneration
• B. Central caseation
• C. Giant cells in the center
• D. Presence of epithelioid cells

Explanation: Tuberculous oral lesions show caseating granulomas containing epithelioid cells and Langhans-type giant cells.

• A. Trigeminal neuraligia
• B. Tetanus
• C. Tuberculous meningitis
• D. Rabies

Explanation: Tetanus causes painful generalized muscle rigidity and masseter spasm, producing trismus or lockjaw.

• A. Measles
• B. Mumps
• C. Tetanus
• D. Scarlet fever

Explanation: Tetanus is infectious but is not transmitted directly from person to person; infection follows contamination of a wound with Clostridium…

• A. Tetany
• B. Actinomycosis
• C. Leprosy
• D. Tetanus

Explanation: Risus sardonicus is the fixed, grimacing facial expression caused by spasms of facial muscles in tetanus.

• A. Ghon complex
• B. Interstitial keratitis
• C. Mulberry molars
• D. Notched incisors

Explanation: Ghon complex is a primary pulmonary tuberculosis lesion, not a feature of congenital syphilis.

• A. Tzanck smear
• B. Direct immunofluorescence
• C. FNAC
• D. Histopathology

Explanation: Direct immunofluorescence in pemphigus vulgaris shows intercellular IgG and C3 in a fish-net or chicken-wire pattern.

• A. Leukoplakia
• B. Syphilis
• C. Lichen planus
• D. Pemphigus

Explanation: Hydropic degeneration of basal keratinocytes, often accompanied by a band-like lymphocytic infiltrate and Civatte bodies, is…

• A. Erythema multiforme
• B. Keratosis follicularis
• C. Psoriasis form lesion
• D. Erythema migrans

Explanation: In oral pathology, erythema migrans refers to geographic tongue, a benign oral mucosal condition with migrating depapillated areas.

• A. Pemphigus
• B. Cicatricial pemphigoid
• C. Bullous pemphigoid
• D. Epidermolysis bullosa acquisita

Explanation: Pemphigus produces intraepithelial, not subepithelial, vesicles because antibodies disrupt desmosomal adhesion between keratinocytes.

• A. Laminin 5
• B. Epiligrin
• C. XVII collagen
• D. BP antigen 1 & 2

Explanation: Collagen XVII, also called BP180, is a basement-membrane-zone antigen targeted in mucous membrane pemphigoid and produces staining on the…

• A. ANUG
• B. Apthous ulcers
• C. Carcinoma in situ
• D. Pemphigus vulgaris

Explanation: PUVA combines a psoralen with UVA exposure and has been used as an adjunctive photochemotherapy option in pemphigus vulgaris.

• A. Tzanck cell
• B. Anitschow cell
• C. Ghost cell
• D. Prickle cell

Explanation: A Tzanck cell is a rounded, swollen epithelial cell produced by acantholysis, classically seen in pemphigus.

• A. Civatte bodies
• B. Max - Joseph spaces
• C. Wickham's Striae
• D. Auspitz's sign

Explanation: Max-Joseph spaces are subepithelial clefts caused by basal-cell degeneration in lichen planus.

• A. Liver, spleen, pancreas
• B. Oral mucosa, lacrimal apparatus, ears
• C. Conjunctive, genitalia, oral mucosa
• D. Parotid gland, palate, conjunctive

Explanation: Stevens-Johnson syndrome characteristically involves mucosal surfaces, especially the oral mucosa, conjunctiva and genital mucosa.

• A. auto immunity
• B. Intercellular oedema
• C. intra epithelial oedema
• D. chronic alcoholism

Explanation: Pemphigus vulgaris is an autoimmune disease in which antibodies against desmosomal proteins, especially desmoglein 3, cause loss of…

• A. pemphigus vegentans
• B. Paraneoplastic pemphigus
• C. Parapemphigus
• D. familial benign pemphigus

Explanation: Paraneoplastic pemphigus is an autoimmune blistering disorder associated with an underlying neoplasm and commonly causes severe mucosal…

• A. Tinel's sign
• B. Bablnski's sign
• C. Nikolsky's sign
• D. Chovstek's sign

Explanation: Nikolsky sign is the formation or extension of a blister when apparently intact epithelium is rubbed or subjected to lateral trauma…

• A. Macule
• B. Bulla
• C. Vesicle
• D. Papule

Explanation: The primary lesion of lichen planus is a small, flat-topped papule, often merging into plaques and showing Wickham striae.

• A. Lichen planus
• B. Erythema multiforme
• C. Pemphigus
• D. Leukoplakia

Explanation: White radiating lines are Wickham striae, the classic surface pattern of lichen planus.