In Cicatrial pemphigoid, which antigen is bound by IgG on the epidermal side of the salt split skin technique:___________?
Correct answer: A. XVII collagen
- A. XVII collagen
- B. Epiligrin
- C. Laminin 5
- D. BP antigen 1 & 2
Explanation
Collagen XVII, also called BP180, is a basement-membrane-zone antigen targeted in mucous membrane pemphigoid and produces staining on the epidermal roof of salt-split skin. Laminin 5, or epiligrin, is associated with binding on the dermal side.
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