Free Oral Mucosal Lesions MCQs with Answers
234 Oral Mucosal Lesions MCQs from Oral Pathology and Medicine, each with the correct answer and a written explanation of why it is correct. Free and unlimited, with no account needed.
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- A. Tzanck smear
- B. Direct immunofluorescence
- C. FNAC
- D. Histopathology
Explanation: Direct immunofluorescence in pemphigus vulgaris shows intercellular IgG and C3 in a fish-net or chicken-wire pattern.
Correct answer: Direct immunofluorescence- A. Leukoplakia
- B. Syphilis
- C. Lichen planus
- D. Pemphigus
Explanation: Hydropic degeneration of basal keratinocytes, often accompanied by a band-like lymphocytic infiltrate and Civatte bodies, is…
Correct answer: Lichen planus- A. Erythema multiforme
- B. Keratosis follicularis
- C. Psoriasis form lesion
- D. Erythema migrans
Explanation: In oral pathology, erythema migrans refers to geographic tongue, a benign oral mucosal condition with migrating depapillated areas.
Correct answer: Erythema migrans- A. Pemphigus
- B. Cicatricial pemphigoid
- C. Bullous pemphigoid
- D. Epidermolysis bullosa acquisita
Explanation: Pemphigus produces intraepithelial, not subepithelial, vesicles because antibodies disrupt desmosomal adhesion between keratinocytes.
Correct answer: Pemphigus- A. Laminin 5
- B. Epiligrin
- C. XVII collagen
- D. BP antigen 1 & 2
Explanation: Collagen XVII, also called BP180, is a basement-membrane-zone antigen targeted in mucous membrane pemphigoid and produces staining on the…
Correct answer: XVII collagen- A. ANUG
- B. Apthous ulcers
- C. Carcinoma in situ
- D. Pemphigus vulgaris
Explanation: PUVA combines a psoralen with UVA exposure and has been used as an adjunctive photochemotherapy option in pemphigus vulgaris.
Correct answer: Pemphigus vulgaris- A. Tzanck cell
- B. Anitschow cell
- C. Ghost cell
- D. Prickle cell
Explanation: A Tzanck cell is a rounded, swollen epithelial cell produced by acantholysis, classically seen in pemphigus.
Correct answer: Tzanck cell- A. Civatte bodies
- B. Max - Joseph spaces
- C. Wickham's Striae
- D. Auspitz's sign
Explanation: Max-Joseph spaces are subepithelial clefts caused by basal-cell degeneration in lichen planus.
Correct answer: Max - Joseph spaces- A. Liver, spleen, pancreas
- B. Oral mucosa, lacrimal apparatus, ears
- C. Conjunctive, genitalia, oral mucosa
- D. Parotid gland, palate, conjunctive
Explanation: Stevens-Johnson syndrome characteristically involves mucosal surfaces, especially the oral mucosa, conjunctiva and genital mucosa.
Correct answer: Conjunctive, genitalia, oral mucosa- A. auto immunity
- B. Intercellular oedema
- C. intra epithelial oedema
- D. chronic alcoholism
Explanation: Pemphigus vulgaris is an autoimmune disease in which antibodies against desmosomal proteins, especially desmoglein 3, cause loss of…
Correct answer: auto immunity- A. pemphigus vegentans
- B. Paraneoplastic pemphigus
- C. Parapemphigus
- D. familial benign pemphigus
Explanation: Paraneoplastic pemphigus is an autoimmune blistering disorder associated with an underlying neoplasm and commonly causes severe mucosal…
Correct answer: Paraneoplastic pemphigus- A. Tinel's sign
- B. Bablnski's sign
- C. Nikolsky's sign
- D. Chovstek's sign
Explanation: Nikolsky sign is the formation or extension of a blister when apparently intact epithelium is rubbed or subjected to lateral trauma…
Correct answer: Nikolsky's sign- A. Macule
- B. Bulla
- C. Vesicle
- D. Papule
Explanation: The primary lesion of lichen planus is a small, flat-topped papule, often merging into plaques and showing Wickham striae.
Correct answer: Papule- A. Lichen planus
- B. Erythema multiforme
- C. Pemphigus
- D. Leukoplakia
Explanation: White radiating lines are Wickham striae, the classic surface pattern of lichen planus.
Correct answer: Lichen planus- A. Lichen planus
- B. Pemphigus vulgari
- C. Bullous pemphigoid
- D. Verrucous vulgaris
Explanation: Pemphigus vulgaris involves IgG autoantibodies against desmosomal proteins in the intercellular cementing substance, producing…
Correct answer: Pemphigus vulgari- A. Leukoedema
- B. Leukoplakia
- C. Lichen planus
- D. Erythema multiformae
Explanation: Wickham's striae are fine, white, lace-like lines produced by lichen planus.
Correct answer: Lichen planus- A. Erythema multiforma
- B. None of the above
- C. SLE
- D. Steven Johnson syndrome
Explanation: Stevens-Johnson syndrome classically causes severe mucosal involvement of the oral, ocular and genital sites, often with skin lesions.
Correct answer: Steven Johnson syndrome- A. Can undergo malignant change
- B. Treated only by medication
- C. Must be excised
- D. Is a idiosyncrasy reaction
Explanation: Lichen planus, particularly persistent erosive disease, carries a small risk of malignant transformation to oral squamous cell carcinoma.
Correct answer: Can undergo malignant change- A. Bullous pemphigoid
- B. pemphigus
- C. Bullous lichen planus
- D. Pemphigoid
Explanation: Pemphigus produces an intraepithelial bulla because autoantibodies disrupt desmosomal adhesion between epithelial cells.
Correct answer: pemphigus- A. Pemphigus vulgaris
- B. Lichenplanus
- C. Erythema multiforme
- D. Psoriasis
Explanation: Target or iris lesions are the hallmark skin lesions of erythema multiforme.
Correct answer: Erythema multiformeOral Mucosal Lesions MCQs: common questions
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There are 234 Oral Mucosal Lesions MCQs in the Oral Pathology and Medicine bank, shown 20 to a page with the correct answer and an explanation on each.
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