Free Substance Use Disorders MCQs with Answers

40 Substance Use Disorders MCQs from Mental Health Nursing, each with the correct answer and a written explanation of why it is correct. Free and unlimited, with no account needed.

Substance use disorders cover problematic use, intoxication, tolerance, dependence, withdrawal, and the effects of alcohol, opioids, sedatives, stimulants, cannabis, and other substances. The topic includes assessment, overdose and withdrawal management, detoxification, motivational interviewing, relapse prevention, and the difference between physical dependence and addiction.

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40 questions · page 1 of 2

  • A. The person needs more of the substance to obtain the same effect
  • B. The person develops symptoms after suddenly stopping the substance
  • C. The person continues use despite repeated social and health problems
  • D. The person experiences intoxication after taking a usual small amount

Explanation: Tolerance means that repeated use causes a reduced response, so larger amounts are needed for the same effect.

Correct answer: The person needs more of the substance to obtain the same effect
Hard
  • A. Offer fluids to prevent dehydration
  • B. Provide airway and ventilatory support and give naloxone
  • C. Place the patient in a quiet room for observation
  • D. Ask the patient about the source of the opioid

Explanation: Severe respiratory depression and cyanosis indicate an immediate breathing emergency.

Correct answer: Provide airway and ventilatory support and give naloxone
Hard
  • A. Mild nausea and reduced appetite
  • B. Fine hand tremor with mild anxiety
  • C. Visual hallucinations with severe agitation and sweating
  • D. Headache with increased sensitivity to light

Explanation: Hallucinations, severe agitation, and marked sweating may indicate severe alcohol withdrawal and progression toward delirium tremens.

Correct answer: Visual hallucinations with severe agitation and sweating
  • A. It usually causes increased appetite and prolonged sleep
  • B. It may cause anxiety, insomnia, tremors, and seizures
  • C. It is safely prevented by stopping the medicine suddenly
  • D. It is treated by giving repeated doses of a stimulant

Explanation: Benzodiazepine withdrawal can produce anxiety, insomnia, tremors, perceptual changes, and seizures.

Correct answer: It may cause anxiety, insomnia, tremors, and seizures
Moderate
  • A. You must stop drinking now or your health will worsen
  • B. Why do you continue drinking when you know it is harmful?
  • C. What changes in your drinking, if any, would you like to consider?
  • D. Your family is correct that you need complete abstinence today

Explanation: Motivational interviewing uses an open, nonjudgmental question that supports patient autonomy and explores readiness for change.

Correct answer: What changes in your drinking, if any, would you like to consider?
  • A. Physical dependence always means the person has lost control of use
  • B. Addiction occurs only when a person has physical withdrawal symptoms
  • C. Physical dependence can cause withdrawal, while addiction includes harmful compulsive use
  • D. Addiction and physical dependence are exactly the same clinical condition

Explanation: Physical dependence is an adaptation that can produce withdrawal when a substance is reduced or stopped.

Correct answer: Physical dependence can cause withdrawal, while addiction includes harmful compulsive use
  • A. Place the patient in a low-stimulation area and monitor cardiac status
  • B. Encourage vigorous exercise to remove the drug from the body
  • C. Give a caffeinated drink to prevent fatigue and sleep
  • D. Leave the patient alone until the effects have completely ended

Explanation: Stimulant intoxication can cause dysrhythmias, myocardial ischemia, hyperthermia, seizures, and severe agitation.

Correct answer: Place the patient in a low-stimulation area and monitor cardiac status
  • A. Slow respirations with pinpoint pupils
  • B. Decreased bowel sounds with marked drowsiness
  • C. Yawning, lacrimation, diarrhea, and enlarged pupils
  • D. Unresponsiveness with cyanosis and weak breathing

Explanation: Opioid withdrawal commonly causes yawning, tearing, runny nose, sweating, abdominal cramps, diarrhea, piloerection, and dilated pupils.

Correct answer: Yawning, lacrimation, diarrhea, and enlarged pupils
Moderate
  • A. To prove that the patient has an alcohol use disorder
  • B. To measure symptoms and guide timely withdrawal treatment
  • C. To determine whether the patient should be discharged immediately
  • D. To replace physical assessment and monitoring of vital signs

Explanation: A structured tool helps quantify withdrawal symptoms and supports timely, consistent treatment according to the facility protocol.

Correct answer: To measure symptoms and guide timely withdrawal treatment
Hard
  • A. I will avoid all people and activities until cravings disappear
  • B. I will handle future cravings alone so I do not burden others
  • C. I will identify a support person and use a planned coping strategy during stress
  • D. I will keep a small supply of the drug in case withdrawal returns

Explanation: Relapse prevention includes identifying triggers, preparing coping responses, and using supportive people or services before a crisis…

Correct answer: I will identify a support person and use a planned coping strategy during stress
  • A. Using the substance occasionally in social settings
  • B. Continuing use despite repeated harmful consequences
  • C. Experiencing mild pleasure after the first use
  • D. Having a family member who uses substances

Explanation: A substance use disorder involves impaired control and continued use despite physical, psychological, or social harm.

Correct answer: Continuing use despite repeated harmful consequences
Easy
  • A. Place the patient in a side-lying position
  • B. Offer coffee to increase alertness
  • C. Encourage the patient to walk around
  • D. Allow the patient to sleep without observation

Explanation: Side-lying positioning helps protect the airway from aspiration when consciousness and the gag reflex are reduced.

Correct answer: Place the patient in a side-lying position
Hard
  • A. Intravenous thiamine administration
  • B. Oral iron supplementation
  • C. Intramuscular vitamin K administration
  • D. Increased dietary calcium intake

Explanation: The findings suggest Wernicke encephalopathy caused by thiamine deficiency.

Correct answer: Intravenous thiamine administration
  • A. Yawning with increased bowel sounds
  • B. Pinpoint pupils with slow breathing
  • C. Dilated pupils with severe sweating
  • D. Tremor with marked anxiety

Explanation: Opioid intoxication commonly causes central nervous system depression, pinpoint pupils, and respiratory depression.

Correct answer: Pinpoint pupils with slow breathing
Hard
  • A. Respiratory rate and level of sedation
  • B. Skin moisture and pupil size only
  • C. Bowel movement frequency and appetite
  • D. Muscle strength and hearing acuity

Explanation: Methadone is a long-acting opioid and may cause excessive sedation and respiratory depression, especially during treatment initiation or…

Correct answer: Respiratory rate and level of sedation
Fairly easy
  • A. Maintain airway support and monitor breathing
  • B. Administer a stimulant drink by mouth
  • C. Keep the patient walking to prevent sleep
  • D. Give an extra sedative to control anxiety

Explanation: Benzodiazepine overdose is managed first with airway, breathing, circulation support and close observation.

Correct answer: Maintain airway support and monitor breathing
  • A. Slow pulse and constricted pupils
  • B. Increased energy with reduced need for sleep
  • C. Slurred speech with poor coordination
  • D. Cold skin with markedly slowed breathing

Explanation: Stimulants commonly produce increased alertness, reduced need for sleep, tachycardia, hypertension, and agitation.

Correct answer: Increased energy with reduced need for sleep
  • A. Cannabis can impair reaction time and judgment
  • B. Cannabis always causes complete unconsciousness
  • C. Cannabis improves coordination at low doses
  • D. Cannabis prevents all memory formation

Explanation: Cannabis may impair attention, reaction time, coordination, and judgment, which makes driving unsafe.

Correct answer: Cannabis can impair reaction time and judgment
  • A. Assess suicide risk repeatedly and provide safety monitoring
  • B. Leave the patient alone to promote uninterrupted sleep
  • C. Give a stimulant medication without a prescription
  • D. Tell the patient that depression is not related to withdrawal

Explanation: Stimulant withdrawal can include a marked depressive phase with fatigue and increased sleep, and suicide risk may change during…

Correct answer: Assess suicide risk repeatedly and provide safety monitoring
Fairly easy
  • A. How much do you use, and when was your last use?
  • B. Why did you make such an unhealthy choice?
  • C. Do you agree that substances are always harmful?
  • D. Can you promise never to use the substance again?

Explanation: A neutral question about amount, frequency, and last use helps determine intoxication risk, withdrawal risk, and immediate treatment…

Correct answer: How much do you use, and when was your last use?

Substance Use Disorders MCQs: common questions

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