Asked in FBISE Biology 2023 — Paper 2 2023Moderate

Hemophilia is more common in males than in females because this trait is

Correct answer: D. Sex linked recessive

  • A. Y-linked recessive
  • B. Sex influenced
  • C. Sex limited
  • D. Sex linked recessive

Explanation

Hemophilia is more common in males because the gene responsible for hemophilia is located on the X chromosome, making it a sex-linked recessive trait. Since males have only one X chromosome, inheriting the recessive allele from their mother leads to hemophilia, whereas females would need to inherit two recessive alleles, one from each parent, which is less likely due to the presence of a dominant allele on the other X chromosome.

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About X-linked Recessive Inheritance

X-linked recessive inheritance involves genes on the X chromosome, so males express a recessive allele with no corresponding allele on their single X chromosome, while females may be carriers. Pedigrees cover haemophilia and red-green colour blindness, including carrier mothers, affected sons and the absence of father-to-son transmission.

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