Free X-linked Recessive Inheritance MCQs with Answers

45 X-linked Recessive Inheritance MCQs from Biology, each with the correct answer and a written explanation of why it is correct. Free and unlimited, with no account needed.

X-linked recessive inheritance involves genes on the X chromosome, so males express a recessive allele with no corresponding allele on their single X chromosome, while females may be carriers. Pedigrees cover haemophilia and red-green colour blindness, including carrier mothers, affected sons and the absence of father-to-son transmission.

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45 questions · page 1 of 3

Moderate
  • A. a man has only one X chromosome, so a single recessive allele is expressed
  • B. the gene lies on the Y chromosome
  • C. the allele is dominant in men and recessive in women
  • D. women lose the allele during meiosis

Explanation: The gene is on the X chromosome and a man is hemizygous, so there is no second copy that could mask a defective allele.

Correct answer: a man has only one X chromosome, so a single recessive allele is expressed
  • A. 0
  • B. one in four
  • C. one in two
  • D. certain

Explanation: A son takes his single X from his mother, and half of her X chromosomes carry the defective allele, so half the sons are colour blind.

Correct answer: one in two
Moderate
  • A. clotting factor VIII
  • B. vitamin K
  • C. platelets
  • D. haemoglobin

Explanation: The X linked recessive gene codes for antihaemophilic factor VIII, and without it the clotting cascade stalls, so even a small injury…

Correct answer: clotting factor VIII
  • A. her mother alone is colour blind
  • B. her father alone is colour blind
  • C. her father is colour blind and her mother is at least a carrier
  • D. neither parent carries the allele

Explanation: A girl has two X chromosomes and needs the recessive allele on both, one from each parent.

Correct answer: her father is colour blind and her mother is at least a carrier
  • A. the ovum, which may carry either an X or a Y chromosome
  • B. the hormones of the mother during pregnancy
  • C. the total number of chromosomes in the zygote
  • D. the sperm, which carries either an X or a Y chromosome

Explanation: The mother is XX and so every ovum carries an X, while the father is XY and produces X bearing and Y bearing sperm in equal numbers, so it…

Correct answer: the sperm, which carries either an X or a Y chromosome
  • A. father to son directly
  • B. mother to daughter only
  • C. father to every one of his sons
  • D. an affected man to his grandsons through his carrier daughters

Explanation: An affected father gives his X, and therefore the allele, to all of his daughters, who become carriers, and half of their sons then…

Correct answer: an affected man to his grandsons through his carrier daughters
Fairly easy
  • A. Autosomal dominant
  • B. Autosomal recessive
  • C. X-linked recessive
  • D. Y-linked

Explanation: Haemophilia is an X-linked recessive disorder affecting blood clotting, more common in males.

Correct answer: X-linked recessive
Fairly easy
  • A. Male with the disorder
  • B. Female with one affected X
  • C. Female with both X affected
  • D. Male without the disorder

Explanation: Carrier females are heterozygous (XAXa) and phenotypically normal but can pass the allele to offspring.

Correct answer: Female with one affected X
  • A. The mother is a carrier and the father is normal
  • B. The mother is hemophiliac and the father is normal
  • C. The mother is carrier and the father is hemophiliac
  • D. Both are normal

Explanation: A girl has two X chromosomes and needs the recessive allele on both, one from each parent, so the father must be haemophiliac himself and…

Correct answer: The mother is carrier and the father is hemophiliac
  • A. 0%
  • B. 25%
  • C. 50%
  • D. 75%

Explanation: A colour blind mother carries the defective allele on both her X chromosomes, and a son receives his only X from her, so every son must be…

Correct answer: 0%
  • A. XY
  • B. XX
  • C. XXY
  • D. XXX

Explanation: In the usual human chromosome pattern, females have two X sex chromosomes, written XX, while males have XY.

Correct answer: XX
  • A. Carrier mother and a colour blind father
  • B. Carrier mother and an unaffected father
  • C. Colour blind mother and an unaffected father
  • D. Unaffected, non-carrier mother and a colour blind father

Explanation: The correct answer is a carrier mother and a color blind father. A carrier mother has one normal X chromosome and one affected X…

Correct answer: Carrier mother and a colour blind father
  • A. Protenor bugs
  • B. Grasshoppers
  • C. Butterflies
  • D. Fruit flies

Explanation: The correct answer is butterflies. In the ZW sex-determination system, which is observed in butterflies, moths, and birds, the female is…

Correct answer: Butterflies
  • A. Option A
  • B. Option B
  • C. Option C
  • D. Option D

Explanation: In the cross mother should be XX, father should be XY and son should be XY. Option D gives the correct representations.

Correct answer: Option D
  • A. Mother is carrier, father is normal
  • B. Mother is hemophiliac, father is normal
  • C. Mother is carrier, father is hemophiliac
  • D. Mother is normal, father is hemophiliac

Explanation: C is the correct option.For a female to have haemophilia, she must inherit an affected X chromosome from each parent.

Correct answer: Mother is carrier, father is hemophiliac
  • A. Red-eyed males
  • B. White-eyed males
  • C. Red-eyed homozygous females
  • D. White-eyed homozygous females

Explanation: Red eye homozygous female is not possible because female will inherit one white eye allele from father. So option C is correct.

Correct answer: Red-eyed homozygous females
  • A. Option A
  • B. Option B
  • C. Option C
  • D. Option D

Explanation: A son must have the genotype XY, with X being inherited from mother and Y from father. Option B correctly represents it.

Correct answer: Option B
  • A. X chromosomes relative to the number of autosomes
  • B. Y chromosomes relative to the number of autosomes
  • C. Autosomes relative to the number of XY chromosomes
  • D. Y chromosomes relative to the number of X chromosomes.

Explanation: In Drosophila, sex determination is based on the ratio of X chromosomes to sets of autosomes (A), rather than the presence of a Y…

Correct answer: X chromosomes relative to the number of autosomes
  • A. He inherited the recessive allele from his mother
  • B. He inherited the dominant allele from his father
  • C. He can pass the disease to a son
  • D. He can pass a dominant allele to a daughter

Explanation: This statement is correct. Since hemophilia is an X-linked recessive disorder, a male with hemophilia inherits the affected X chromosome…

Correct answer: He inherited the recessive allele from his mother
  • A. Beard growth
  • B. Baldness
  • C. Haemophilia
  • D. Tfm

Explanation: Testicular feminization, also known as androgen insensitivity syndrome (AIS), is a genetic condition in which individuals with XY…

Correct answer: Tfm

X-linked Recessive Inheritance MCQs: common questions

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