Asked in FBISE Biology 2022 — Paper 2 2022

Which one is a sex-limited trait?

Correct answer: D. Tfm

  • A. Beard growth
  • B. Baldness
  • C. Haemophilia
  • D. Tfm

Explanation

Testicular feminization, also known as androgen insensitivity syndrome (AIS), is a genetic condition in which individuals with XY chromosomes are resistant to the effects of androgens, such as testosterone. As a result, affected individuals are born with external female genitalia despite having male chromosomes. This condition is caused by mutations in the gene encoding the androgen receptor (AR) located on the X chromosome. Because the condition only affects individuals with a Y chromosome, it is considered a sex-limited trait.

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About X-linked Recessive Inheritance

X-linked recessive inheritance involves genes on the X chromosome, so males express a recessive allele with no corresponding allele on their single X chromosome, while females may be carriers. Pedigrees cover haemophilia and red-green colour blindness, including carrier mothers, affected sons and the absence of father-to-son transmission.

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