A man has hemophilia. Which statement correctly describes the inheritance of this gene?
Correct answer: A. He inherited the recessive allele from his mother
- A. He inherited the recessive allele from his mother
- B. He inherited the dominant allele from his father
- C. He can pass the disease to a son
- D. He can pass a dominant allele to a daughter
Explanation
This statement is correct. Since hemophilia is an X-linked recessive disorder, a male with hemophilia inherits the affected X chromosome from his mother who carries the recessive allele. Females need two copies of the recessive allele to express the disorder, while males only need one because they have only one X chromosome.
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About X-linked Recessive Inheritance
X-linked recessive inheritance involves genes on the X chromosome, so males express a recessive allele with no corresponding allele on their single X chromosome, while females may be carriers. Pedigrees cover haemophilia and red-green colour blindness, including carrier mothers, affected sons and the absence of father-to-son transmission.
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