Asked in Premeth Test 6 — Biological Molecules, Genetics, Transport and Digestion (8 March 2025) 2025Moderate

Which of the following options is correct for pattern baldness?

Correct answer: B. Occurs due to hormonal differences between sexes

  • A. It is a sex-linked trait
  • B. Occurs due to hormonal differences between sexes
  • C. Heterozygous male is normal
  • D. Homozygous female is normal

Explanation

Pattern baldness, also known as androgenic alopecia, is influenced by hormonal differences, specifically the effects of androgens (male hormones such as testosterone) on hair follicles. While it is not strictly a sex-linked trait, it is more common in males due to their higher levels of these hormones.Why the other options are incorrect:It is a sex-linked trait: Pattern baldness is not directly inherited through the X or Y chromosomes (i.e., it is not a sex-linked trait). It is primarily influenced by autosomal genes and hormonal activity.Heterozygous male is normal: Males have only one X chromosome, so they cannot be heterozygous for pattern baldness. If they inherit the baldness allele, they will be affected.Heterozygous female is normal: Females have two X chromosomes, so if they inherit one allele for baldness, they are typically carriers and usually not affected, as the trait is influenced by the dominant allele and hormonal factors.

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About X-linked Recessive Inheritance

X-linked recessive inheritance involves genes on the X chromosome, so males express a recessive allele with no corresponding allele on their single X chromosome, while females may be carriers. Pedigrees cover haemophilia and red-green colour blindness, including carrier mothers, affected sons and the absence of father-to-son transmission.

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