All Free Pharmacology MCQs with Answers

• A. Antifungal agent
• B. Antibacterial
• C. Antiviral agent
• D. Chemotherapic agent

Explanation: Ketoconazole is an imidazole antifungal that inhibits fungal ergosterol synthesis by blocking 14-alpha-demethylase.

• A. Interfere with metabolism
• B. Inhibition of protein synthesis
• C. Inhibition of cell wall formation
• D. Interfere with DNA function

Explanation: Chlortetracycline, like other tetracyclines, binds the 30S ribosomal subunit and prevents aminoacyl-tRNA attachment, thereby inhibiting…

• A. Ampicillin
• B. Sulbactum
• C. Cloxacillin
• D. Pencillin G

Explanation: Sulbactam is a beta-lactamase inhibitor that is combined with beta-lactam antibiotics to protect them from enzymatic hydrolysis.

• A. Skin rash
• B. Intersititial Nephritis
• C. Drug fever
• D. Encephalopathy

Explanation: Penicillin-induced encephalopathy is dose related and is more likely with high intravenous doses or impaired renal clearance.

• A. Ulcerative gingivitis
• B. Amoebiasis
• C. Trichomonas infection
• D. Streptococcal sore throat

Explanation: Metronidazole treats anaerobic infections, amoebiasis and trichomoniasis, and may be used in ulcerative gingivitis.

• A. Tetracycline
• B. Lincomycin
• C. Clindamyclin
• D. Penicillin G

Explanation: Tetracyclines reach gingival crevicular fluid and can concentrate around periodontal tissues, which supports their use in selected…

• A. Ciprofloxacin
• B. Chloroquin
• C. Mebendazole
• D. Bephenium Naphthoate

Explanation: Chloroquine is used as a luminal or hepatic adjunct after metronidazole to eradicate amoebae in the liver and reduce relapse in amoebic…

• A. Nystatin
• B. Bacitracin
• C. Penicillin
• D. Tetracycline

Explanation: Nystatin binds ergosterol in Candida cell membranes and is effective locally in the mouth because it is not significantly absorbed from…

• A. Ritonavir
• B. Saquinavir
• C. Nelfinavir
• D. Zanamivir

Explanation: Ritonavir, saquinavir and nelfinavir inhibit HIV protease, whereas zanamivir inhibits influenza neuraminidase and prevents release of new…

• A. Tetracyclines
• B. Aminoglycosides
• C. Quinalones
• D. Macrolides

Explanation: Aminoglycosides can damage the vestibulocochlear system, causing ototoxicity, and accumulate in renal tubular cells, causing…

• A. Penicillin
• B. Demeclocycline
• C. Erythormycin
• D. Streptomycin

Explanation: Demeclocycline, a tetracycline, can cause photosensitivity because the drug absorbs ultraviolet light and promotes photochemical skin…

• A. Ceftum
• B. Ciprofloxacin
• C. Clindamycin
• D. Erythromycin

Explanation: Clindamycin penetrates and concentrates well in bone and other hard tissues, making it useful for certain bone and dental infections.

• A. Oral antibiotic
• B. Topical antibiotic
• C. Parenteral antibiotic
• D. All of the above

Explanation: Bacitracin is too nephrotoxic for routine systemic or parenteral use, so it is used mainly as a topical antibiotic for superficial skin…

• A. Broad spectrum antibiotic
• B. Quinolone
• C. Imidazole derivative
• D. Antidepressant

Explanation: Metronidazole is a nitroimidazole, commonly described in basic pharmacology questions as an imidazole derivative.

• A. Lincomycin
• B. Penicillin
• C. Cephalexin
• D. Ampicillin

Explanation: Penicillins and cephalexin inhibit bacterial peptidoglycan cross-linking and therefore block cell-wall synthesis.

• A. Ethambutol
• B. Isoniazid
• C. Streptomycin
• D. Kanamycin

Explanation: Streptomycin is generally the least nephrotoxic aminoglycoside, although it has important vestibular ototoxicity.

• A. Calcification
• B. Missing teeth
• C. Discolored teeth
• D. Peg teeth

Explanation: Tetracyclines bind calcium in developing teeth and bones, producing permanent yellow-brown or gray tooth discoloration.

• A. It is broad spectrum antibiotic
• B. It has anticollagenolytic effect
• C. All of the above
• D. None of the aboveCompare Prescription Prices

Explanation: Tetracyclines are useful in periodontics because they cover relevant periodontal bacteria and inhibit collagenase, reducing…

• A. Candidiasis
• B. Photosensitivity
• C. Bone marrow depression
• D. Angioneurotic oedema

Explanation: The most serious chloramphenicol toxicity is dose-independent aplastic anemia, reflecting severe bone-marrow suppression.

• A. Dapsone
• B. Streptomycin
• C. Clofazimine
• D. Ethambutol

Explanation: Clofazimine has anti-inflammatory activity and is particularly useful for controlling erythema nodosum leprosum and other lepra reactions.