All Free Pharmacology MCQs with Answers

• A. Reduce the risk allergic reactions:
• B. Prolong amoxicillin's half-life
• C. Reduce the severity of diarrhea
• D. Extend amoxicillin's antibacterial spectrum

Explanation: Clavulanic acid irreversibly inhibits many bacterial beta-lactamases, protecting amoxicillin from enzymatic destruction.

• A. Norfloxacin
• B. Streptomycin
• C. Doxycycline
• D. Cefotaxime

Explanation: Aminoglycosides such as streptomycin can enhance neuromuscular blockade produced by d-tubocurarine, causing prolonged paralysis or…

• A. Transcription mechanisms
• B. Translation
• C. Ribosomal function
• D. PABA

Explanation: Sulfonamides are structural analogues of PABA and competitively inhibit its incorporation into dihydrofolic acid, blocking bacterial…

• A. Acyclovir
• B. Vidarabine
• C. Idoxyuridine
• D. Ara-amp

Explanation: Acyclovir selectively inhibits herpesvirus DNA polymerase after activation in infected cells, making it both potent and relatively…

• A. Accumulate in renal failure
• B. Inhibit protein synthesis
• C. Effective against gram negative infection
• D. All of the above

Explanation: Aminoglycosides inhibit bacterial protein synthesis at the 30S ribosomal subunit, are especially useful against aerobic Gram-negative…

• A. Cidal in action
• B. Cidal in high concentration
• C. Static in action
• D. All of these

Explanation: Erythromycin is usually bacteriostatic at therapeutic concentrations but can become bactericidal at high concentrations against…

• A. Clindamycin
• B. Penicillin
• C. Tetracyline
• D. Metronidazole

Explanation: Tetracyclines concentrate in gingival crevicular fluid and can reach levels higher than those in serum, supporting their use against some…

• A. Methicillin
• B. Ampicillin
• C. Penicillin V
• D. Cefixime

Explanation: Ampicillin has a broader Gram-negative spectrum than penicillin V and methicillin, including activity against organisms such as…

• A. Sulphonamide
• B. Chloramphenicol
• C. Ethambutol
• D. Rifampin

Explanation: Sulfonamides, chloramphenicol, and ethambutol are primarily bacteriostatic, whereas rifampin inhibits bacterial RNA polymerase and is…

• A. It is an antitubercular drug
• B. It can be given orally
• C. Effective against g-ve organisms
• D. None of the above

Explanation: Streptomycin is used in tuberculosis treatment and has activity against several Gram-negative organisms, but it is poorly absorbed from…

• A. Cotrimoxazole
• B. Furazolidone
• C. Nalidixic acid
• D. Ceftriaxone

Explanation: Ceftriaxone is not a standard oxidant drug associated with haemolysis in G6PD deficiency, whereas cotrimoxazole, furazolidone and…

• A. Scabies
• B. Intestinal nematode infection
• C. Filariasis
• D. All of the above

Explanation: Ivermectin is a broad antiparasitic drug used for scabies, several intestinal nematode infections and filariasis.

• A. Sulphonamide
• B. Tetracycline
• C. Ampicillin
• D. Cholarmphenicol

Explanation: Ampicillin is a penicillin and may trigger an allergic reaction in a patient with penicillin hypersensitivity.

• A. Antileprotic drugs
• B. Antitubercular drugs
• C. Streptomycin
• D. Chloramphenicol

Explanation: Streptomycin, an aminoglycoside used in tuberculosis, can cause vestibular or cochlear ototoxicity and may produce perioral or circumoral…

• A. There is less deposition in dentine as compared to enamel
• B. Is always accompanied by hypolastic defects
• C. Stains are dark brown in color
• D. Stained teeth fluoresce light yellow under U.V light

Explanation: Tetracycline becomes incorporated into developing teeth and produces yellow fluorescence under ultraviolet light, later becoming…

• A. Enthionamide
• B. INH
• C. Ethambutol
• D. Pyrazinamide

Explanation: Isoniazid can cause neuropsychiatric adverse effects, including impaired concentration and transient memory disturbance, in addition to…

• A. Penicilline-V is more stable gastric acid
• B. Penicilline-G is more absorbed from the G.I.T
• C. Penicilline-G is more allergic than penicillin-V
• D. None of the above

Explanation: Penicillin V is more resistant to gastric acid, so it can be given orally with better stability.

• A. Gentamicin
• B. Ciprofloxacin
• C. Metronidazole
• D. Linezolid

Explanation: Metronidazole was the traditional drug of choice for initial Clostridioides difficile colitis and remains the expected answer in older…

• A. Zidovodine
• B. Acyclovir
• C. Nystatin
• D. Amontidine

Explanation: Acyclovir selectively inhibits herpesvirus DNA polymerase after activation by viral thymidine kinase, giving it useful antiviral activity…

• A. Primaquine is liable to cause hemolysis in patients with G6PD deficiency
• B. Halofantrine prolongs QT interval and causes dysarrythmia
• C. Mefloquine may safely be given to air pilots
• D. Primaquine eliminates P. vivax and P. ovale

Explanation: Mefloquine can cause dizziness, vestibular disturbance and neuropsychiatric effects, so it is unsuitable for air pilots and other…