Moderate

All of the following statement about antimalarial drugs are correct except_____________?

Correct answer: C. Mefloquine may safely be given to air pilots

  • A. Primaquine is liable to cause hemolysis in patients with G6PD deficiency
  • B. Halofantrine prolongs QT interval and causes dysarrythmia
  • C. Mefloquine may safely be given to air pilots
  • D. Primaquine eliminates P. vivax and P. ovale

Explanation

Mefloquine can cause dizziness, vestibular disturbance and neuropsychiatric effects, so it is unsuitable for air pilots and other safety-sensitive workers. Primaquine can cause haemolysis in G6PD deficiency, halofantrine can prolong QT, and primaquine eradicates dormant liver forms of P. vivax and P. ovale.

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