All Free Pharmacology MCQs with Answers

• A. codeine
• B. Methadone
• C. Alphaprodine
• D. Pentazocine

Explanation: Methadone is a long-acting opioid used for opioid-substitution treatment because it prevents withdrawal and reduces craving without the…

• A. Contraindicated
• B. Low safety
• C. Can be used safely
• D. Not much useTry Prep Courses

Explanation: Barbiturates have a narrow therapeutic index, so respiratory depression and excessive sedation make them relatively low-safety drugs in…

• A. Meprobamate
• B. Pentobarbital
• C. Trimethadione
• D. Phenytoin

Explanation: Phenytoin is a classic treatment for generalized tonic-clonic, or grand mal, seizures because it limits sustained high-frequency neuronal…

• A. Antibiotics
• B. Salicylates
• C. Barbiturates
• D. Phenothiazines

Explanation: Phenothiazines block dopamine D2 receptors in the nigrostriatal pathway, causing extrapyramidal symptoms such as dystonia, akathisia and…

• A. Folic acid deficiency
• B. Alzhiemer's disease
• C. Cushing's syndrome
• D. Vitamin C deficiencyConsult Online Doctors

Explanation: Phenytoin increases folate metabolism and can reduce folic acid levels during long-term treatment, sometimes causing megaloblastic…

• A. D-tubocurarin
• B. Diazepam
• C. Beclofen
• D. Mephensin

Explanation: D-tubocurarine produces skeletal muscle relaxation by blocking nicotinic receptors at the neuromuscular junction, which is a peripheral…

• A. Antibiotic
• B. Sedative
• C. Tricyclic antidepressant
• D. DiureticCompare Prescription Prices

Explanation: Amitriptyline is a tricyclic antidepressant that inhibits the reuptake of noradrenaline and serotonin.

• A. Excretion
• B. Metabolism
• C. Redistribution
• D. Recycling

Explanation: Thiopentone rapidly leaves the brain and redistributes to muscle and fat, so its anaesthetic action ends before significant metabolism…

• A. Produce muscle relaxation
• B. Alter psychotic behaviour
• C. Suppress coughing
• D. Produce analgesia

Explanation: Phenothiazines such as chlorpromazine and fluphenazine are antipsychotic drugs used to reduce psychotic symptoms by blocking dopamine D2…

• A. Buspirone
• B. Nitrazepam
• C. Zopiclone
• D. Diazepam

Explanation: Buspirone is a non-benzodiazepine anxiolytic that generally does not produce significant sedation, psychomotor impairment or dependence.

• A. Naloxone
• B. Nalosphine
• C. Nalpuphine
• D. Methadine

Explanation: Naloxone is a competitive opioid-receptor antagonist that rapidly reverses morphine-induced respiratory and central nervous system…

• A. Remifentanil
• B. Morphine
• C. Sufentanil
• D. Fentanyl

Explanation: Morphine, fentanyl and sufentanil are established neuraxial opioids, whereas remifentanil is not routinely given intrathecally because of…

• A. Analgesia is associated with μ and k receptors
• B. Dysphoria is associated with S receptors
• C. NSAIDS benefit by preventing prostaglandin synthesis
• D. Naloxane is a non-competitive antagonist and irreversibly opposes the opioids

Explanation: Naloxone is a competitive, reversible opioid antagonist, not a noncompetitive irreversible antagonist.

• A. Reye's syndrome
• B. Nausea
• C. Diarrhoea
• D. Acid-base imbalance

Explanation: Aspirin use during viral infections in children is associated with Reye syndrome, an acute encephalopathy with hepatic dysfunction.

• A. Aspirin
• B. Ibuprufen
• C. Diclofenac potassium
• D. Mefenamic acid
• E. Both A & B

Explanation: Aspirin and other nonselective NSAIDs, including ibuprofen, can precipitate bronchospasm in aspirin-sensitive asthma through increased…

• A. Limbic system
• B. Emetic system
• C. Chemoreceptor trigger zone (CTZ)
• D. Opioid receptors in G.I.T

Explanation: Opioids stimulate the medullary chemoreceptor trigger zone, producing nausea and vomiting.

• A. Drowsiness
• B. Gastric irritation
• C. Xerostomia
• D. Constipation

Explanation: NSAIDs reduce protective gastric prostaglandins and can directly irritate the gastric mucosa, making gastric irritation a common class…

• A. Benzodiazepam is used in treatment of status epilepticus
• B. Benzodiazepam is used in the long term treatment of psychic disorders
• C. Clonazeppam is used in the treatment of petitmal epilepsy
• D. None of the above

Explanation: Diazepam is used acutely for status epilepticus and clonazepam can treat absence seizures, but benzodiazepines are generally not used for…

• A. Morphine
• B. Fentanyl
• C. Remifentanil
• D. Sufentanil

Explanation: Remifentanil is rapidly hydrolysed by nonspecific blood and tissue esterases, giving it an exceptionally short context-sensitive…

• A. Increase BT
• B. Increase CT
• C. Increase PTT
• D. Increase APTT

Explanation: Aspirin irreversibly inhibits platelet cyclooxygenase and thromboxane A2 formation, impairing platelet aggregation and prolonging bleeding…