All Free Pathology MCQs with Answers

• A. Fibroblast
• B. Macrophages
• C. Polymorphs
• D. Budding blood vessels

Explanation: The essential components of granulation tissue are proliferating fibroblasts, newly formed capillaries and inflammatory cells such as…

• A. Steroids
• B. Protein
• C. Vitamin C
• D. Adequate oxygen supply

Explanation: Protein, vitamin C and adequate oxygen support collagen synthesis and tissue repair.

• A. Distal end
• B. Proximal end
• C. Both A and B
• D. None of the above

Explanation: After nerve transection, axonal sprouts arise from the viable proximal stump and may grow toward the distal segment.

• A. Both of the above
• B. Secondary union
• C. Primary union
• D. None of the above

Explanation: Primary bony union may occur by direct healing with medullary or endosteal bone formation and little or no periosteal callus.

• A. Infection
• B. Cortisol
• C. Foreign Bodies
• D. All of the aboveConsult Online Doctors

Explanation: Infection, glucocorticoids such as cortisol, and retained foreign bodies all delay healing by sustaining inflammation or suppressing…

• A. Implantation cyst
• B. Keloid
• C. Wound dehiscence
• D. Cicatrisation

Explanation: Entrapped epithelial cells can continue to proliferate and form an implantation cyst after wound closure.

• A. Cicatrisation
• B. Primary healing
• C. Secondary healing
• D. RegenerationConsult Injury Lawyers

Explanation: Large wounds with tissue loss cannot have their edges directly approximated, so they heal by secondary intention with abundant granulation…

• A. Giant cells
• B. Fibroblasts
• C. Endothelial cells
• D. B & C

Explanation: Granulation tissue is made mainly of proliferating capillaries lined by endothelial cells and fibroblasts producing extracellular matrix.

• A. Fibroblasts
• B. Myofibroblasts
• C. Vitamin C
• D. Vitamin D

Explanation: Fibroblasts produce collagen, myofibroblasts cause wound contraction, and vitamin C is required for collagen hydroxylation and strength.

• A. 1
• B. 2
• C. 0.5
• D. 5

Explanation: Peripheral axons generally regenerate at approximately 1 mm per day, provided the connective-tissue pathway and neuron remain viable.

• A. Remodeling of bone
• B. Formation of fibrous joint or pseudoarthrosis
• C. Formation of blood clot
• D. Formation of procallus or osseous cells

Explanation: A fibrous joint or pseudoarthrosis represents failure of bony union, whereas a clot, procallus, and subsequent remodeling are normal…

• A. Hormones
• B. Blood supply
• C. Growth factors
• D. Collagen

Explanation: Collagen provides the tensile strength of a healing wound, with strength increasing as collagen is deposited and remodelled.

• A. Wound contraction
• B. Inflammatory response
• C. Epithelial changes
• D. Formation of blood clot

Explanation: Wound contraction is prominent in secondary intention because the larger tissue defect requires myofibroblasts to pull the edges together.

• A. Secondary intention
• B. Primary intention
• C. Cicatrisation
• D. All of the above

Explanation: A clean surgical wound whose edges are closely approximated with sutures heals by primary intention, with minimal tissue loss…

• A. Coagulative necrosis
• B. Caesous necrosis
• C. Fibrinoid necrosis
• D. Fatty necrosis

Explanation: Fibrinoid necrosis is a smudgy, intensely eosinophilic vascular deposit formed from necrotic tissue mixed with immune complexes…

• A. Midline lethal granuloma
• B. Sarcoidosis
• C. Leprosy
• D. Tuberculosis

Explanation: Caseous necrosis is the characteristic necrosis of tuberculosis, producing a soft, cheese-like appearance within granulomas.

• A. Tumor marker
• B. Proto oncogene
• C. Oncogene
• D. Bacterial antigen

Explanation: PSA is produced by prostatic epithelial cells and is measured clinically to help detect and monitor prostate carcinoma, making it a tumour…

• A. Choristoma
• B. Plemorphic tumours
• C. Teratoma
• D. Hamartoma

Explanation: A teratoma contains tissues derived from two or more germ layers, often including ectoderm, mesoderm and endoderm.

• A. Cytotoxic T - lymphocytes
• B. Natural killer cells
• C. Humoral mechanism
• D. All of the above

Explanation: Tumour immunity involves cytotoxic T lymphocytes, natural killer cells and antibody-mediated or other humoral mechanisms.

• A. Modified melanocytes
• B. Cells containing excessive melanin pigment
• C. Melangocytes which are functionally more active
• D. large melanocytes

Explanation: Nevus cells are modified melanocytes that form benign melanocytic nevi.