All Free Pathology MCQs with Answers

Every Pathology question in the bank, across all chapters, each with the correct answer and a written explanation. Free and unlimited, with no account needed.

289 questions · page 15 of 15

  • A. jaundice
  • B. Haemosiderosis
  • C. Kernicterus
  • D. All of the above

Explanation: Kernicterus is bilirubin deposition in the basal ganglia and other brain regions, usually in severe neonatal unconjugated…

Correct answer: Kernicterus
  • A. Scanning electron miscroscopy
  • B. Electron microscopy
  • C. X-ray crytallography
  • D. Polarized microscopy

Explanation: Amyloid is confirmed with Congo red staining showing apple-green birefringence under polarized light.

Correct answer: Polarized microscopy
  • A. Increase in osteoid maturation time
  • B. Decrease in osteoid surface
  • C. Decrease in osteoid volume
  • D. Increase in mineral apposition rate

Explanation: Osteomalacia is defective mineralization of newly formed osteoid, so osteoid maturation time increases and mineral apposition falls.

Correct answer: Increase in osteoid maturation time
  • A. Actinomycosis
  • B. Tuberculosis
  • C. Rabies
  • D. Secondary Iues

Explanation: Secondary amyloidosis is caused by prolonged inflammation or infection, and tuberculosis is a classic underlying disease.

Correct answer: Tuberculosis
  • A. Hydropic degeneration
  • B. Amyloid degeneration
  • C. Hyaline degeneartion
  • D. Fatty degeneration

Explanation: Mallory-Denk bodies are eosinophilic cytoplasmic aggregates of damaged intermediate filaments in hepatocytes.

Correct answer: Hyaline degeneartion
  • A. AL protein
  • B. a2 microglobulin
  • C. a-amyloid protein
  • D. Transthyretin

Explanation: Senile systemic amyloidosis is caused by deposition of wild-type transthyretin, especially in the heart of older adults.

Correct answer: Transthyretin
  • A. Spleen
  • B. Kidney
  • C. Liver
  • D. Heart

Explanation: The kidney is the commonest and often clinically most important site of systemic amyloid deposition, where it can cause proteinuria and…

Correct answer: Kidney
  • A. Hodgkin's diseaes
  • B. Tuberculosis
  • C. Multiple myeloma
  • D. Chronic osteomyelitis

Explanation: Primary amyloidosis is usually caused by a plasma-cell disorder producing monoclonal immunoglobulin light chains, and it is classically…

Correct answer: Multiple myeloma
  • A. Reticulin
  • B. Masson's toichrome
  • C. Vonkosa
  • D. Congo Red

Explanation: Congo red is the standard stain for amyloid and shows apple-green birefringence under polarized light.

Correct answer: Congo Red