Free Oral Manifestations of Systemic Disease MCQs with Answers

• A. Iron deficiency
• B. Vitamin C deficiency
• C. Folate deficiency
• D. Protein deficiency

Explanation: Folate deficiency impairs DNA synthesis, producing megaloblastic anaemia with large, immature red-cell precursors.

• A. RNA paramyxo virus
• B. Varicella zoster virus
• C. Coxsackie virus A 16
• D. Epstein Barr virus

Explanation: Infectious mononucleosis is most commonly caused by Epstein-Barr virus, a DNA herpesvirus.

• A. Ulcers which bruise easily
• B. Multiple draining sinuses
• C. Palatal perforation
• D. Alveolar bone loss

Explanation: Infectious mononucleosis may produce oral ulceration and petechial or bruising-like lesions, especially on the palate, because of its…

• A. Pernicious anemia
• B. Infectious mononucleosis
• C. Sickle cell anemia
• D. Leukemia

Explanation: The Monospot test detects heterophile antibodies and is used as a rapid test for infectious mononucleosis.

• A. It can cause abvious prupura
• B. It may be manifested by mucosal pallor
• C. It characteristically causes gross gingival swelling
• D. It is usually of the lymphoblastic variety

Explanation: Acute childhood leukaemia is commonly acute lymphoblastic leukaemia, and pallor and purpura reflect marrow failure and thrombocytopenia.

• A. Vit - C deficiency
• B. Thrombocytopenia
• C. Vit - K deficiency
• D. Heamophilia

Explanation: Hemarthrosis, or bleeding into joints, is classically associated with haemophilia because deficient clotting factors impair secondary…

• A. Chediak higashi syndrome
• B. chronic granulocytic leukemia
• C. lazy leukocyte syndrome
• D. alukemic leukemia

Explanation: Chediak-Higashi syndrome causes partial oculocutaneous hypopigmentation, silvery or gray hair, abnormal neutrophil granules, recurrent…

• A. IX
• B. VIII
• C. X
• D. VI

Explanation: The recurrent hemarthrosis and family history indicate haemophilia A, an X-linked deficiency of factor VIII.

• A. cyclic neutropenia
• B. agranulocytosis
• C. pernicious anemia
• D. thrombocytopenic purpura

Explanation: Thrombocytopenic purpura causes petechiae and other mucocutaneous bleeding because the platelet count is reduced.

• A. Von Willebrand's disease
• B. Haemophilia
• C. Henoch Schenolein purpura
• D. Telangiectasia

Explanation: Von Willebrand disease prolongs bleeding time because platelet adhesion is impaired through deficiency or dysfunction of von Willebrand…

• A. Leucocytosis
• B. Agranulocytosis
• C. Sickle cell anemia
• D. Polycythemia vera

Explanation: Agranulocytosis produces severe necrotising oral ulcers with little surrounding inflammation because neutrophils are markedly depleted.

• A. insufficient production of red cells
• B. can be correct by tablets of folic acid alone
• C. Improper maturation of red cells
• D. can be correct by iron supplement

Explanation: Pernicious anemia is a vitamin B12-deficiency megaloblastic anemia in which impaired DNA synthesis causes defective or improper maturation…

• A. Infectious mononucleosis
• B. Multiple myeloma
• C. Malignant nerves
• D. Rubella

Explanation: The Paul-Bunnell test detects heterophile antibodies, which are classically produced in infectious mononucleosis caused by Epstein-Barr…

• A. Whole blood
• B. Factor VIII concentrate
• C. Fresh frozen plasma
• D. Factor IX concentrate

Explanation: Haemophilia A is factor VIII deficiency, so perioperative bleeding is prevented or treated with factor VIII concentrate.

• A. Thrombocytosis
• B. Increased prothrombin time
• C. Increased bleeding time
• D. Increased clotting time

Explanation: ITP is caused by immune platelet destruction, so the platelet count falls and primary haemostasis is impaired, producing an increased…

• A. Bleeding into soft tissues, muscles and joints
• B. Decreased factor VIII
• C. Increase Partial thromboplastin Time
• D. Increase prothrombin Time

Explanation: Haemophilia A is a factor VIII deficiency that prolongs the intrinsic pathway, giving an increased partial thromboplastin time.

• A. Microcytic and Hypochromic
• B. Macrocytic and normochromic
• C. Normocytic and hypochromic
• D. Normocytic and normochromic

Explanation: Reduced globin-chain production in beta thalassemia produces small red cells with reduced haemoglobin content, hence microcytic…

• A. It is associated with palatelet-specific auto-antibodies
• B. It causes more prolonged hemorrhage than hemophilia
• C. It is often controlled by immunosuppressive treatment
• D. It caused a prolonged bleeding time

Explanation: ITP commonly causes mucocutaneous bleeding with prolonged bleeding time and is treated with immune-modifying therapy because platelet…

• A. Herpes
• B. measles
• C. Diphtheria
• D. leishmaniasis

Explanation: Diphtheria is caused by Corynebacterium diphtheriae, a bacterium, and may produce an adherent oral or pharyngeal pseudomembrane.

• A. Blastomycosis
• B. Cat scratch fever
• C. Sarcoidosis
• D. Streptococcus pneumonia

Explanation: Multinucleated giant cells occur in granulomatous or chronic inflammatory lesions such as blastomycosis, cat-scratch disease and…