Free Oral Manifestations of Systemic Disease MCQs with Answers

• A. All of the above
• B. Obtain WBC count
• C. Obtain platelet count
• D. Consult physician

Explanation: Before extracting a tooth from a patient with leukaemia, the physician should be consulted and the white-cell and platelet counts checked…

• A. Chromosomal deletion
• B. Chromosomal mutation
• C. Chromosomal translocation
• D. None of the above

Explanation: Chronic granulocytic, or myeloid, leukaemia is characteristically associated with the Philadelphia chromosome, produced by a reciprocal…

• A. Enlarged tongue
• B. Focal marrow expansion
• C. Generalized osteolysis
• D. Atrophic glossitis

Explanation: Nutritional anaemias commonly produce a smooth, sore tongue with loss of papillae, called atrophic glossitis, especially in iron or…

• A. Glandular involvement
• B. Febrile
• C. Palatine Petechiae
• D. All of the above

Explanation: Infectious mononucleosis commonly causes fever, lymphoid or glandular enlargement, and palatal petechiae due to the systemic Epstein-Barr…

• A. All of the above
• B. agranulocytosis
• C. liver cirrhosis
• D. influenza

Explanation: Leucocytopenia may occur with influenza, agranulocytosis and advanced liver cirrhosis, often through marrow suppression or splenic…

• A. Ecchymosis
• B. Melanosis
• C. Petechiae
• D. Purpura

Explanation: Ecchymosis, petechiae and purpura are caused by blood escaping into tissues, whereas melanosis is melanin pigmentation and is not a…

• A. Vitamin K
• B. Monsel's solution
• C. Factor 8 cryoprecipitate
• D. Aminocaproic acid

Explanation: Aminocaproic acid inhibits fibrinolysis and helps preserve postoperative clots, making it useful after surgery in haemophilic patients.

• A. Factor IX deficiency
• B. Factor VII deficiency
• C. Platelet deficiency
• D. it C deficiency

Explanation: Haemophilia B, or Christmas disease, results from deficiency of clotting factor IX. Haemophilia A is the related factor VIII deficiency.

• A. Acquired immunodeficiency syndrome (AIDS)
• B. Infection mononucleosis
• C. Primary syphilis
• D. Recurrent apthous stomatitis

Explanation: Infectious mononucleosis is called the kissing disease because Epstein-Barr virus is commonly transmitted through saliva.

• A. Folic acid deficiency
• B. Plummer-Vinson syndrome
• C. Pernicious anaemia
• D. Paterson-Kelly syndrome

Explanation: Pernicious anaemia can cause neurological manifestations from vitamin B12 deficiency and may be associated with premature greying of hair.

• A. Fibrous dysplasia
• B. Pagets disease
• C. Garre's Osteomyelitis
• D. Thalassemia

Explanation: Thalassaemia causes marrow expansion as the body increases erythropoiesis, producing a hair-on-end or crew-cut appearance on skull…

• A. Pigmented teeth
• B. Hypoplastic teeth
• C. Dentinal dysplasia
• D. All of the above

Explanation: Erythroblastosis fetalis may produce green or brown pigmentation of developing teeth, often with enamel hypoplasia and structural defects.

• A. Codominant
• B. Autosomal recessive
• C. Autosomal dominan
• D. X-Linked recessive

Explanation: The commonest form of von Willebrand disease, type 1, is usually inherited as an autosomal dominant disorder with variable expression.

• A. Chronic ITP commonly occur in adult women
• B. Increased megakaryocytes in bone marrow
• C. Prothrombin Time (PT) & Partial Thromboplastin Time (PTT) are normal
• D. Associated with normal bleeding time

Explanation: ITP causes thrombocytopenia, so bleeding time is prolonged, while PT and PTT are usually normal and marrow megakaryocytes are increased.

• A. Transparency of root
• B. Cementum apposition
• C. Attrition
• D. Root resorption

Explanation: Root transparency is regarded as the most reliable Gustafson criterion for adult dental age estimation because it increases relatively…

• A. Factor IX deficiency
• B. Factor VIII deficiency
• C. Factor X deficiency
• D. Vitamin K deficiency

Explanation: Haemophilia A results from factor VIII deficiency, while von Willebrand disease involves defective von Willebrand factor with reduced…

• A. Erythroblastosis fetalis
• B. Aplatic anemia
• C. Thalassemia
• D. Pernicious anemia

Explanation: Cooley anaemia is the severe form of beta-thalassaemia major, caused by markedly reduced beta-globin production.

• A. Rh (D) immunoglobulin
• B. Blocking antibody
• C. Antilymphocyte globulin
• D. Antithymocyte serum

Explanation: Anti-D Rh immunoglobulin given to an Rh-negative mother prevents sensitisation to Rh-positive fetal red cells and thereby reduces…

• A. Tourniquet time
• B. Prothrombin time
• C. Clotting time
• D. Bleeding time

Explanation: Warfarin inhibits vitamin K-dependent clotting factors and is monitored with prothrombin time, reported clinically as the INR.

• A. Tetracycline
• B. Cephalosporin
• C. Chloramphenicol
• D. Penicillin

Explanation: Chloramphenicol is classically associated with rare, unpredictable, and potentially fatal aplastic anaemia due to bone-marrow suppression.