Chronic granulocytic leukemia is due to______________?
Correct answer: C. Chromosomal translocation
- A. Chromosomal deletion
- B. Chromosomal mutation
- C. Chromosomal translocation
- D. None of the above
Explanation
Chronic granulocytic, or myeloid, leukaemia is characteristically associated with the Philadelphia chromosome, produced by a reciprocal chromosomal translocation between chromosomes 9 and 22. This creates the BCR-ABL fusion gene.
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