Hypopigmentation, gray streaks of hair, degranulation defect of neutrophils and neuropathy are seen in_____________?
Correct answer: A. Chediak higashi syndrome
- A. Chediak higashi syndrome
- B. chronic granulocytic leukemia
- C. lazy leukocyte syndrome
- D. alukemic leukemia
Explanation
Chediak-Higashi syndrome causes partial oculocutaneous hypopigmentation, silvery or gray hair, abnormal neutrophil granules, recurrent infections and neurological features. The neutrophil defect is due to impaired lysosomal degranulation.
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