Free Antimicrobial Drugs MCQs with Answers
50 Antimicrobial Drugs MCQs from Nursing Pharmacology, each with the correct answer and a written explanation of why it is correct. Free and unlimited, with no account needed.
Antimicrobial pharmacology covers antibiotics, antitubercular, antifungal, antiviral and antiparasitic drugs, including their targets, clinical uses, resistance and major adverse effects. Questions distinguish bactericidal from bacteriostatic action, narrow from broad spectrum therapy, and antimicrobial treatment from supportive management of infection.
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50 questions · page 3 of 3
- A. They bind to the 30S ribosomal subunit
- B. They block bacterial cell wall cross-linking
- C. They inhibit fungal ergosterol synthesis
- D. They prevent viral nucleic acid release
Explanation: Aminoglycosides bind to the 30S ribosomal subunit and cause faulty bacterial protein synthesis.
Correct answer: They bind to the 30S ribosomal subunit- A. Stop the medicine and seek urgent medical review
- B. Give the next dose with extra water
- C. Apply a moisturiser and continue treatment
- D. Reassure the patient that this is an expected effect
Explanation: Blistering skin and mucosal sores may indicate Stevens-Johnson syndrome, a serious drug reaction.
Correct answer: Stop the medicine and seek urgent medical review- A. Use an additional non-hormonal contraceptive method
- B. Take both medicines at the same time each morning
- C. Double the contraceptive dose during tuberculosis therapy
- D. Stop rifampicin whenever menstrual bleeding occurs
Explanation: Rifampicin increases hepatic metabolism of hormonal contraceptives and can reduce their effectiveness.
Correct answer: Use an additional non-hormonal contraceptive method- A. Take each dose with food containing some fat
- B. Take each dose only on an empty stomach
- C. Avoid all fluids for two hours after each dose
- D. Take the tablets together with an antacid
Explanation: Lumefantrine is absorbed better when artemether-lumefantrine is taken with food containing fat, such as milk or a meal.
Correct answer: Take each dose with food containing some fat- A. Vancomycin
- B. Gentamicin
- C. Benzylpenicillin
- D. Acyclovir
Explanation: Oral vancomycin acts within the intestinal tract and is commonly used for C. difficile infection.
Correct answer: Vancomycin- A. Clean and dry the area before applying a thin layer
- B. Cover the area tightly with an airtight dressing
- C. Stop the cream as soon as itching decreases
- D. Apply the cream only to visibly broken skin
Explanation: The affected skin should be cleaned and dried before a thin layer is applied, and treatment should continue for the prescribed duration.
Correct answer: Clean and dry the area before applying a thin layer- A. Serotonin syndrome
- B. Acute iron poisoning
- C. Hypoglycaemic shock
- D. Red man syndrome
Explanation: Linezolid can increase serotonergic activity when combined with some antidepressants, causing serotonin syndrome.
Correct answer: Serotonin syndrome- A. Praziquantel
- B. Oseltamivir
- C. Fluconazole
- D. Isoniazid
Explanation: Praziquantel is an antiparasitic drug commonly used against schistosome infections.
Correct answer: Praziquantel- A. Intravenous artesunate
- B. Oral albendazole
- C. Topical permethrin
- D. Oral nystatin
Explanation: Severe falciparum malaria requires prompt parenteral antimalarial treatment, with intravenous artesunate commonly recommended.
Correct answer: Intravenous artesunate- A. Fluoroquinolones
- B. Macrolides
- C. Aminoglycosides
- D. Sulfonamides
Explanation: Fluoroquinolones inhibit DNA gyrase and topoisomerase IV, preventing bacterial DNA replication.
Correct answer: Fluoroquinolones