How do aminoglycoside antibiotics such as gentamicin mainly affect bacteria?
Correct answer: A. They bind to the 30S ribosomal subunit
- A. They bind to the 30S ribosomal subunit
- B. They block bacterial cell wall cross-linking
- C. They inhibit fungal ergosterol synthesis
- D. They prevent viral nucleic acid release
Explanation
Aminoglycosides bind to the 30S ribosomal subunit and cause faulty bacterial protein synthesis. Cell wall cross-linking is mainly affected by beta-lactam antibiotics.
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About Antimicrobial Drugs
Antimicrobial pharmacology covers antibiotics, antitubercular, antifungal, antiviral and antiparasitic drugs, including their targets, clinical uses, resistance and major adverse effects. Questions distinguish bactericidal from bacteriostatic action, narrow from broad spectrum therapy, and antimicrobial treatment from supportive management of infection.
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