Which antimicrobial drug class inhibits bacterial DNA gyrase and topoisomerase IV?
Correct answer: A. Fluoroquinolones
- A. Fluoroquinolones
- B. Macrolides
- C. Aminoglycosides
- D. Sulfonamides
Explanation
Fluoroquinolones inhibit DNA gyrase and topoisomerase IV, preventing bacterial DNA replication. Macrolides and aminoglycosides act on bacterial ribosomes, while sulfonamides inhibit folate synthesis.
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About Antimicrobial Drugs
Antimicrobial pharmacology covers antibiotics, antitubercular, antifungal, antiviral and antiparasitic drugs, including their targets, clinical uses, resistance and major adverse effects. Questions distinguish bactericidal from bacteriostatic action, narrow from broad spectrum therapy, and antimicrobial treatment from supportive management of infection.
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