Free AIDS and HIV Infection MCQs with Answers

49 AIDS and HIV Infection MCQs from Biology, each with the correct answer and a written explanation of why it is correct. Free and unlimited, with no account needed.

HIV is a retrovirus that infects CD4 T lymphocytes and gradually weakens immune function, while AIDS is the advanced syndrome caused by severe immune deficiency. Coverage includes viral transmission, replication, disease progression, opportunistic infections, diagnosis, prevention and the difference between HIV infection and AIDS.

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49 questions · page 1 of 3

  • A. helper T lymphocytes carrying the CD4 receptor
  • B. red blood cells
  • C. neutrophils in the bone marrow
  • D. platelets in circulating blood

Explanation: The gp120 spike of HIV binds the CD4 receptor, so helper T cells are the main target, and these are the cells that activate both B…

Correct answer: helper T lymphocytes carrying the CD4 receptor
Moderate
  • A. carries double stranded DNA as its genome
  • B. uses reverse transcriptase to make DNA from its RNA genome
  • C. replicates inside the nucleolus of the host cell
  • D. lacks an envelope around its capsid

Explanation: A retrovirus reverses the usual flow of information: its enzyme reverse transcriptase copies the single stranded RNA genome into DNA…

Correct answer: uses reverse transcriptase to make DNA from its RNA genome
  • A. Sharing a contaminated hypodermic needle
  • B. From an infected mother to her child during breastfeeding
  • C. Shaking hands with or sharing utensils with an infected person
  • D. Transfusion of blood from an infected donor

Explanation: HIV is fragile outside the body and spreads only through blood, semen, vaginal secretions and breast milk, so ordinary social contact…

Correct answer: Shaking hands with or sharing utensils with an infected person
  • A. antibodies against HIV first appear in the blood
  • B. the provirus enters the latent phase
  • C. reverse transcriptase is detected in the plasma
  • D. the CD4 count falls below about 200 cells per microlitre and opportunistic infections appear

Explanation: AIDS is the late clinical stage, defined by the collapse of helper T cell numbers to roughly a fifth of normal together with opportunistic…

Correct answer: the CD4 count falls below about 200 cells per microlitre and opportunistic infections appear
Fairly easy
  • A. ELISA
  • B. Widal test
  • C. ABO blood grouping
  • D. Routine urine analysis

Explanation: ELISA detects antibodies against HIV and is cheap and sensitive enough for mass screening, with a positive result confirmed afterwards by…

Correct answer: ELISA
Moderate
  • A. Typhoid fever
  • B. Pneumocystis pneumonia
  • C. Malaria
  • D. Cholera

Explanation: Pneumocystis jirovecii causes pneumonia almost only in people whose cell mediated immunity has failed, so it is one of the defining…

Correct answer: Pneumocystis pneumonia
  • A. dissolving the lipid envelope of the virus
  • B. stimulating plasma cells to make more antibody
  • C. inhibiting the enzyme reverse transcriptase
  • D. killing the infected helper T cells before the virus matures

Explanation: AZT is a nucleoside analogue that reverse transcriptase inserts into the growing DNA chain, after which the chain cannot be extended, so…

Correct answer: inhibiting the enzyme reverse transcriptase
  • A. Measles
  • B. Influenza
  • C. Hepatitis A
  • D. AIDS

Explanation: AIDS destroys or severely weakens CD4 helper T cells, reducing immune coordination and allowing opportunistic infections to develop.

Correct answer: AIDS
  • A. helper-T
  • B. B
  • C. both T and B
  • D. none of these

Explanation: HIV mainly infects helper T lymphocytes because the virus attaches to the CD4 receptor on these cells, gradually weakening specific…

Correct answer: helper-T
  • A. HAV
  • B. HIV
  • C. Rabies
  • D. Pigs

Explanation: AIDS is caused by human immunodeficiency virus, or HIV, which progressively damages immune cells, especially CD4 T lymphocytes.

Correct answer: HIV
  • A. SsRNA
  • B. DsRNA
  • C. SsDNA
  • D. DsDNA

Explanation: HIV is an enveloped single-stranded RNA virus and is a retrovirus because it uses reverse transcriptase to make DNA from its RNA genome.

Correct answer: SsRNA
  • A. Polio
  • B. Hepatitis
  • C. AIDS
  • D. HIV

Explanation: AIDS is the advanced syndrome caused by HIV, involving severe immune deficiency and opportunistic problems such as pneumonia, lymph-node…

Correct answer: AIDS
  • A. is a host specific disease
  • B. An infected mother cannot pass the virus to her baby.
  • C. Results in enlargement of lymph nodes
  • D. Can be prevented.

Explanation: An infected mother can transmit HIV to her baby during pregnancy, childbirth, or breastfeeding, so that statement is incorrect.

Correct answer: An infected mother cannot pass the virus to her baby.
  • A. HAV
  • B. HBV
  • C. HCV
  • D. HEV

Explanation: HCV commonly persists after the initial infection and can cause chronic hepatitis, cirrhosis and hepatic failure.

Correct answer: HCV
  • A. Envelope
  • B. RNA
  • C. Reverse Transcriptase
  • D. All of these

Explanation: The envelope of a virus is derived from the host cell's membrane during the process of viral budding.

Correct answer: Envelope
  • A. Uncoating
  • B. Reverse Transcription
  • C. Provirus Integration
  • D. Assembly

Explanation: The provirus is the integrated viral DNA in the host cell genome, and its formation involves the reverse transcription process in the…

Correct answer: Provirus Integration
  • A. B lymphocytes
  • B. Helper T lymphocytes
  • C. Cytotoxic T lymphocytes
  • D. Memory cells
  • E. Macrophages

Explanation: Explanation for this question will be added soon.

Correct answer: Helper T lymphocytes
  • A. Male
  • B. Female
  • C. AIDS patient
  • D. Athletes

Explanation: Aspergillosis occurs in humans, birds, and other animals. Aspergillosis occurs in chronic or acute forms which are clinically very…

Correct answer: AIDS patient
  • A. Measles
  • B. Influenza
  • C. Hepatitis A
  • D. AIDS

Explanation: a. Measles: Measles weakens the immune system, making individuals more susceptible to opportunistic infections.

Correct answer: AIDS
  • A. It is a retrovirus
  • B. It is surrounded by an envelope
  • C. It does not cause AIDS
  • D. It causes deficiency of the human immune system

Explanation: It is a well known fact that HIV virus does cause AIDS.

Correct answer: It does not cause AIDS

AIDS and HIV Infection MCQs: common questions

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