Moderate

Which vector can clone only a small fragment of DNA?

Correct answer: C. Plasmid

  • A. Bacterial artificial chromosome
  • B. Yeast artificial chromosome
  • C. Plasmid
  • D. Cosmid

Explanation

Plasmids have been modified to be used as vectors. They can clone DNA fragments of about 10 kbp size while cosmid can carry up to 45 kbp. Yeast artificial chromosome can carry up to 1000-­2500 kbp. Bacterial artificial chromosome can carry around 300 - 350 kbp long DNA fragments. A kilobase pair (kbp) is a unit of length of nucleic acids, equal to 1000 base pairs

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