Which of the following processes is used in the conversion of pyruvate to acetyl-CoA?

Correct answer: D. Both A and C

  • A. Decarboxylation
  • B. Dehydration
  • C. Dehydrogenation
  • D. Both A and C

Explanation

The conversion of pyruvate to acetyl-CoA is a crucial step in cellular respiration. It involves the removal of a carbon atom from pyruvate, which is released as carbon dioxide, a process known as decarboxylation. Simultaneously, the remaining two-carbon fragment undergoes dehydrogenation, where hydrogen atoms are transferred to NAD+, forming NADH. Therefore, both decarboxylation and dehydrogenation are essential to this conversion. Options A and C describe parts of the process, but only option D correctly identifies that both processes occur in tandem.

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Cellular respiration explains how cells release energy from glucose through glycolysis, the link reaction, Krebs cycle and electron transport chain. It includes ATP production, substrate-level and oxidative phosphorylation, aerobic versus anaerobic respiration, and the roles of mitochondria, oxygen and fermentation in energy transfer.

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