Starting from the end products of glycolysis, how many molecules of CO₂ are produced up to the formation of succinate in a single Krebs cycle?

Correct answer: A. 1

  • A. 1
  • B. 2
  • C. 3
  • D. 4

Explanation

Starting from pyruvate, the end product of glycolysis, 1 molecule of CO₂ is released up to the formation of succinate in a single turn of the Krebs cycle. This carbon dioxide is produced during the conversion of pyruvate to acetyl-CoA by the pyruvate dehydrogenase complex. No additional CO₂ is released in the Krebs cycle itself before succinate is formed, as the decarboxylation steps that generate more CO₂ occur later, after succinate formation. Therefore, the correct number of CO₂ molecules released up to succinate is one. Options suggesting 0 are incorrect because pyruvate decarboxylation does produce CO₂, while options suggesting 2 or 3 are incorrect because they count CO₂ released in steps that occur after succinate formation.

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