Before pyruvate enters the citric acid cycle, it is decarboxylated, oxidized, and combined with coenzyme A, forming acetyl-CoA, carbon dioxide, and one molecule of:

Correct answer: A. NADH

  • A. NADH
  • B. FADH2
  • C. ATP
  • D. ADP

Explanation

Before entering the citric acid cycle, pyruvate undergoes a preparatory step where it is decarboxylated and oxidized, resulting in the formation of acetyl-CoA, carbon dioxide, and NADH. NADH is created when NAD+ is reduced, capturing electrons released during the oxidation of pyruvate. FADH2, ATP, and ADP are not products of this specific conversion; FADH2 is generated in later stages of the citric acid cycle, while ATP and ADP are involved in energy transfer processes elsewhere in cellular respiration.

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Cellular respiration explains how cells release energy from glucose through glycolysis, the link reaction, Krebs cycle and electron transport chain. It includes ATP production, substrate-level and oxidative phosphorylation, aerobic versus anaerobic respiration, and the roles of mitochondria, oxygen and fermentation in energy transfer.

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