Before entering the Krebs cycle, the pyruvate is decarboxylated into
Correct answer: D. Acetyl-CoA
- A. α-ketoglutaric acid
- B. Glyceric acid
- C. Citric acid
- D. Acetyl-CoA
Explanation
Glycolysis results in the formation of pyruvate, which is transported into the mitochondria. Here, the pyruvate is decarboxylated and oxidized to form acetyl-CoA, a reaction catalyzed by the pyruvate dehydrogenase complex. Acetyl-CoA is the correct substrate that enters the Krebs cycle. Other options, such as α-ketoglutaric acid, glyceric acid, and citric acid, are either intermediates or products of different processes within cellular respiration and are not directly formed from pyruvate decarboxylation.
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About Bioenergetics
Cellular respiration explains how cells release energy from glucose through glycolysis, the link reaction, Krebs cycle and electron transport chain. It includes ATP production, substrate-level and oxidative phosphorylation, aerobic versus anaerobic respiration, and the roles of mitochondria, oxygen and fermentation in energy transfer.
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